Results 61 to 70 of about 2,134,463 (264)
Will There Be a Science of Law in the Twenty-First Century? [PDF]
, 1991 The skepticism of the American Legal Realists and their heirs threatens to make a politically neutral science of law impossible and thus to undermine the liberal polity which needs such a science. Ronald Dworkin attempts to refute the skeptics and defend
Stith, Richard
core +2 more sources
Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis
Advanced Science, EarlyView.The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li +12 more
wiley +1 more source
Advanced Science, EarlyView.The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang +8 more
wiley +1 more source
The “Constitution in Exile” as a Problem for Legal Theory [PDF]
, 2014 How does one defend a constitutional theory that’s out of the mainstream? Critics of originalism, for example, have described it as a nefarious “Constitution in Exile,” a plot to impose abandoned rules on the unsuspecting public.
Sachs, Stephen E.
core +2 more sources
Advanced Science, EarlyView.Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo +12 more
wiley +1 more source
Raça, escravidão e liberdade na história do direito
Rechtsgeschichte - Legal History, 2021 review on: Alejandro de la Fuente, Ariela J. Gross, Becoming Free, Becoming Black: Race, Freedom, and Law in Cuba, Virginia, and Louisiana, Cambridge / New York: Cambridge University Press 2020, 295 p., ISBN 978-1-108-48064 ...
Bruno Lima
doaj +1 more source
The Jurisprudential Turn in Legal Ethics [PDF]
, 2011 When legal ethics developed as an academic discipline in the mid-1970s, its theoretical roots were in moral philosophy. The early theorists in legal ethics were moral philosophers by training, and they explored legal ethics as a branch of moral ...
Kruse, Katherine R.
core +2 more sources
International law as primitive accumulation: Or, the secret of systematic colonization [PDF]
, 2012 This article is available open access through the publisher’s website at the link below. Copyright © The Author, 2012.This article aims to bring the category of ‘primitive accumulation’ into the vocabulary of critical and Marxist international legal ...
Neocleous, M
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Advanced Science, EarlyView.Super‐resolution microscopy identifies nano‐sized tau aggregates (nano‐aggregates) and reveals distinct transitions in their morphology and phosphorylation profiles across control, Primary Age‐Related Tauopathy, and Alzheimer's disease brains. Morphology and hyperphosphorylation signatures distinguish physiological from pathological forms, with nano ...
Adriana N. Santiago‐Ruiz +5 more
wiley +1 more source
German Law JournalThis Article examines the evolving concept of the material constitution and its application to the EU. The first part focuses on the theory of Italian jurist Costantino Mortati, exploring both its foundations and its contemporary relevance.
Leonardo Ravaioli
doaj +1 more source