Results 201 to 210 of about 986,928 (308)

Stakeholder Perspectives on Affinity Domains in Digital Health Interoperability: Qualitative Study.

JMIR Med Inform
Bruthans J, Hospodková P, Fejfarová I.
europepmc   +1 more source

Evaluating AI decision tools in Ecuador's courts: efficiency, consistency, and uncertainty in legal judgments. [PDF]

Front Artif Intell
Rodríguez-Salcedo E, Martínez-Bonilla C, Pérez-Mayorga B, Salame-Ortiz M, Armas-Freire P, Espín-Miniguano A, Pino-Loza E.   +6 more
europepmc   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Development and Validation of the Future Career Insecurity Scale (FCIS) in Law Students. [PDF]

Behav Sci (Basel)
Lan C, Weng X, Huang QL, Yu L, Wang R, Su J, Zhou T, Lou T, Li Y, Li W.   +9 more
europepmc   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Quantifying climate loss and damage consistent with a social cost of carbon. [PDF]

Nature
Burke M, Zahid M, Diffenbaugh NS, Hsiang S.   +3 more
europepmc   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

The vulnerability of refugees and asylum seekers in Italy: Insights from a nationwide survey. [PDF]

PLoS One
Mendola D, Cela E, Ortensi LE, Ambrosini M, Arcaio M, Barbiano di Belgiojoso E, Busetta A, Impicciatore R, Miaci E, Parigi M, Parroco AM, Stranges M, Tosi F.   +12 more
europepmc   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

How to Teach Generative Artificial Intelligence in Undergraduate Medical Education. [PDF]

Clin Teach
Feigerlova E.
europepmc   +1 more source