Results 81 to 90 of about 2,684,738 (314)
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Temporal Aspects of Smart Contracts for Financial Derivatives
Implementing smart contracts to automate the performance of high-value over-the-counter (OTC) financial derivatives is a formidable challenge. Due to the regulatory framework and the scale of financial risk if a contract were to go wrong, the performance
C Clack, D Magazzeni, N Rescher, RM Lee
core +1 more source
Two internal critiques of political constitutionalism [PDF]
The antagonism between legal and political constitutionalism has almost monopolized the discussion on constitutional theory during the last years.
Goldoni, M.
core +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Legitimacy as the sign of the right
Legitimacy constructed and constituts society, including the right to. Here possible conclusion, that legitimacy is the feature of the law. However not all agree with this point.
I. L. Chestnov
doaj
Law as an innovative system: theoretical approach
The subject of the study is the extrapolation of the main provisions of innovation to the legal form of social existence. The purpose of the article is to disclose and systematize the key elements of understanding law as an innovative system.Methodology.
M. V. Shugurov, A. A. Vasiliev
doaj +1 more source
What do we mean by legal justice, as opposed to distributive, or social, or political justice; what is the justice, that is, we hope law promotes? What is the justice that lawyers and judges, peculiarly, are professionally committed to pursue?
West, Robin
core +1 more source
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
Animals, Slaves, and Corporations: Analyzing Legal Thinghood [PDF]
The Article analyzes the notion of legal “thinghood” in the context of the person–thing bifurcation. In legal scholarship, there are numerous assumptions pertaining to this definition that are often not spelled out.
Kurki, Visa A. J.
core

