Results 171 to 180 of about 4,115 (300)

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu   +14 more
wiley   +1 more source

From manners to rules ::advocating for legalism in South Korea and Japan /

open access: yes
From Manners to Rules traces the emergence of legalistic governance in South Korea and Japan. While these countries were previously known for governance characterized by bureaucratic discretion and vague laws, activists and lawyers are pushing for a more
Arrington, Celeste L.,
core   +1 more source

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

open access: yesAdvanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye   +15 more
wiley   +1 more source

\u3ci\u3eThe Politics of Legalism\u3c/i\u3e

open access: yes, 1991
Prentice Avery Meador, Jr.\u27s sermon, The Politics of Legalism. This sermon was preached Sunday evening, January 13, 1991, at Prestoncrest Church of Christ in Dallas ...
Meador, Prentice Avery, Jr.
core  

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou   +21 more
wiley   +1 more source

No Law Is an Island: A Dialogical Rejoinder to Authoritarian Legalism

open access: yes
A new form of “autocratic legalism” (Scheppele) that relies on law rather than guns raises a serious challenge to democratic constitutionalism. While authors tend to focus on the “illiberal” challenge, this article is concerned with its jurisprudential ...
Etxabe, Julen
core   +1 more source

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