Results 101 to 110 of about 13,475 (268)
Revista Facultad Nacional de Salud Pública, 2008 Revista Facultad Nacional de Salud Pública - Página legal.
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Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome
Advanced Science, EarlyView.We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu +19 more
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G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
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Making Drones Illegal Based on a Wrong Example: The U.S. Dronified Warfare
Türkiye Ortadoğu Çalışmaları Dergisi, 2016 Dronelaştırılmış savaş (dronified warfare), ABD'nin Terörle Mücadele Stratejisinde belirlemeye başlayan, teknolojinin, eğlencenin ve ordunun bir karışımından ortaya çıkan yeni savaş türü oldu.
Gloria Shkurti
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On the Requirements of Legal Justice of the Administrative Law Enforcement Activity
Сибирское юридическое обозрение, 2020 The article considers issues of understanding by the administrative-legal science of legal justice of the law-enforcement activity of executive authorities, other public administration bodies.
S. V. Yarkovoy
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Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
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Competitive Legal Professionals' use of Technology in Legal Practice and Legal Research
Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese Regsblad, 2008 Advances in the information and communication technologies have led to the availability of a range of primary and secondary legal research publications online via the Internet, rather than on other storing devices such as compact discs or publications in the print media.
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Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
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LEGITIMACY AND LEGALITY OF REVOLUTION IN THE THEORETICAL THOUGHT OF EDMUND BURKE
PravoWithin legal doctrine, a longstanding debate has persisted as to whether revolution may be regarded as a legitimate and lawful means of altering state authority. From the perspective of a democratic constitutional order, revolution constitutes a violent
Predrag Terzić
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Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
Advanced Science, EarlyView.In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
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