Results 251 to 260 of about 1,047,959 (349)

Author Correction: Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21. [PDF]

Nature
Ranade SS, Li F, Whalen S, Pelonero A, Ye L, Huang Y, Brand A, Nishino T, Mital R, Boileau RM, Koback F, Padmanabhan A, Yu V, Cimarosti B, Presas-Ramos D, Merriman AF, Wallace LG, Nguyen A, Poulis N, Costa MW, Gifford CA, Pollard KS, Srivastava D.   +22 more
europepmc   +1 more source

The Legend of Sleepy Hollow [PDF]

Irving, Washington
core  

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Extensive myocardial calcification following cytokine release syndrome and sepsis: a novel case report with advanced echocardiographic assessment. [PDF]

Eur Heart J Case Rep
Canales-Muñoz L, Ugueto-Rodrigo C, Rodríguez-Carneiro C, Lara-García A, Diaz-González L, Moreno R.   +5 more
europepmc   +1 more source

The legend of R. Yehuda Halevi's death : truth or fiction [PDF]

, 2009
Brodt, Eliezer
core  

Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications

Advanced Science, EarlyView.
Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo, Lorena de Oñate, Maximillian Frank, Xian Hu, Sophie M. Blackburn, Dana V. Foss, Jasmine Villegas, Kunica Asija, Dirk Hockemeyer, Hongxia Fu, Raymond J. Monnat, Ross C. Wilson, Benjamin S. Freedman   +12 more
wiley   +1 more source

Ectopic Cushing Syndrome Due to a Large Mediastinal Neuroendocrine Tumor. [PDF]

JCEM Case Rep
Ramírez-García JA, Garza-García G, Mehta R, Reza-Albarrán AA, De La Peña-López R, Iñiguez-Ariza NM.   +5 more
europepmc   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Scenario-aware control of multipathway spread processes: Application to biological invasions. [PDF]

PNAS Nexus
Sambaturu P, Sudhir M, Chen H, Vullikanti A, Muniappan R, Adiga A.   +5 more
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source