Results 271 to 280 of about 1,047,959 (349)

Melchizedek Legend of 2 (Slavonic) Enoch [PDF]

, 2000
Orlov, Andrei
core   +1 more source

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Advanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih, Nicolas L.A. Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P. Moritz, Yannick Tholance, Jean‐Philippe Camdessanché, Jean‐Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François‐Moutal, Aubin Moutal   +12 more
wiley   +1 more source

Recurrent myocarditis as a clinical gateway to desmoplakin cardiomyopathy: a case report. [PDF]

Eur Heart J Case Rep
Reyes T RE, Vargas-Hernández DA, Cañón DP, Figueroa JF.   +3 more
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Notes on Collection and Research, Part 2

Scottish Studies, 1963
[Editor]
doaj  

Erratum in: Relative Myopic Defocus in the Superior Retina as an Indicator of Myopia Development in Children. [PDF]

Invest Ophthalmol Vis Sci
europepmc   +1 more source

A pilot morphometric analysis of lumbar vertebrae to identify fluoroscopic biomarkers. [PDF]

Interv Pain Med
Tran J, Chau E, Calleja M, Leekam R, Loh E.   +4 more
europepmc   +1 more source

PDZK1‐ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reveals that PDZK1 loss impairs ULK1‐mediated lipophagy, driving lipid droplet accumulation and sunitinib resistance in clear cell renal cell carcinoma. PDZK1 inhibits LEF1 nuclear translocation, enhancing ULK1 transcription. Pharmacological ULK1 activation resensitizes resistant tumors to sunitinib.
Xuan Qi, Yu Guo, Yumeng Yang, Haibo Wang, Xiaomei Yang, Ran Song, Qiong Qin, Yan Zhang, Meihan Hu, Haixing Zhou, Duiping Feng, Junqi He   +11 more
wiley   +1 more source

Myth and the Legends of Lowland Scottish Saints

Scottish Studies, 1980
John MacQueen
doaj  

Case report of extensive embolic complications in culture-negative mitral valve endocarditis due to <i>Rothia dentocariosa</i>. [PDF]

Eur Heart J Case Rep
Lam HYW.
europepmc   +1 more source