Results 41 to 50 of about 329,483 (266)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

A Noah of Our Days: Around Him Mythologies Arose

open access: yesCoolabah, 2009
From the pages of Thomas Keneally’s best seller, Schindler’s Ark, emerges the seductive figure of a modern hero of mythical proportions, the German Oskar Schindler who rescued over 1000 Jews from the hands of the Nazis and certain death. This Noah of our
Elisa Morera de la Vall
doaj   +1 more source

The Verse about the Holy Mountain by Vyacheslav Ivanov: a Close Reading. Second Essay [PDF]

open access: yesStudia Litterarum, 2018
This article addresses the problems of dating “The Verse about the Holy Mountain,” by Vyacheslav Ivanov, the origin and the meaning of the epigraph, and establishes the connection between the poem and the topic of Kiev.
Andrey L. Тоporkov
doaj   +1 more source

The legend of the KJU

open access: yesKorean Journal of Urology, 2015
The Korean Journal of Urology (KJU) will change its name starting in 2016. Recently, the editorial board of the KJU had a spirited discussion about whether to keep the original name or change it to attract more international authors and readers of our journal. In 2014, approximately 60% of the papers submitted to the KJU were from outside of Korea, and
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Bailar con el diablo: metamorfosis de una leyenda oral, del Abruzzo italiano a la literatura de cordel de Brasil

open access: yesBoletín de Literatura Oral, 2019
This article presents different oral versions, for the most part unpublished, on the Dancing With the Devil legend. The author tries to outline, through a comparative analysis, the sequences and motifs found in this type of legend. The topic variants and
Cruz Carrascosa
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Myth and One-Dimensionality

open access: yesHumanities, 2017
A striking difference between the folk-narrative genres of legend and folktale is how the human characters respond to supernatural, otherworldly, or uncanny beings such as ghosts, gods, dwarves, giants, trolls, talking animals, witches, and fairies.
William Hansen
doaj   +1 more source

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