Results 31 to 40 of about 184,704 (269)
In this article, I edit and analyze an oral legend that was communicated to me by don Luis Marín (b. 1943), great repository of the oral tradition of Guanajuato (Mexico) in 2018.
Gabriel Medrano de Luna
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Вилка Л. Радужный храм детства: жизнь и творчество Зирки Мензатюк. В статье анализируется творческое наследие известной украинской детской писательницы Зирки Мензатюк. Мы хронологически рассматриваем рост ее как автора, анализируем лучшие ее творческие
Lidiya VYLKA
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The article related to the journal cover is dealing with the legend of Aquarius and open-pit Erzberg.
openaire +3 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Supernatural Beings of Belief Legends – Old Fears in a New Context
This paper examines the use of belief legends about witches, werewolves, and fairies at open-air festivals in Croatia today. At such events, traditions based on belief legends are invented with the idea of enriching local tourism not only as a source of ...
Luka Šešo
doaj +1 more source
HISTORICAL MYTHOLOGY IN THE FIRST LITTLE RUSSIAN SHORT STORY OF N. GOGOL “EVENING ON THE EVE OF IVAN KUPALA” [PDF]
The article deals with Nikolai Gogol’s first novel “Evening on the Eve of Ivan Kupala” (1830), and studies the difference between its early and canonical editions, that argues for an attempt of an emerging author to create the “poetic history” of the ...
Vladimir D. Denisov
doaj +1 more source

