Results 71 to 80 of about 510,453 (307)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Nucleon-nucleon scattering within a multiple subtractive renormalization approach [PDF]

, 2011
A methodology to renormalize the nucleon-nucleon interaction, using a recursive multiple subtraction approach to construct the kernel of the scattering equation, is presented.
A. Delfino, G. P. Lepage, L. Tomio, Lauro Tomio, S. Weinberg, T. Frederico, V. S. Timóteo   +6 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Zwisima na zwipise ndi fhethu ha zwifho: traditional hydrological knowledge, conservation and protection of groundwater among the Venda, northern South Africa

Frontiers in Human Dynamics
Springs are vital freshwater and hydrothermal groundwater sources. We pose the research question how springs are perceived in indigenous worldview and employ ethnographic and historical sources highlighting springs as sacred sites protected by myths and ...
Munyadziwa Magoma, Innocent Pikirayi
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

American Myths, Legends, and Tall Tales: An Encyclopedia of American Folklore

, 2016
Folklore has been a part of American culture for as long as humans have inhabited North America, and increasingly formed an intrinsic part of American culture as diverse peoples from Europe, Africa, Asia, and Oceania arrived.
Dattolo, Danielle R., Fee, Christopher R., Fetters, Bronwen, Francisco, Emily A., Hillegonds, Jaime, Webb, Jeffrey, Wickersham, Andrew   +6 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Legends of the lakes of Wales : thematic classification and analysis. [PDF]

, 2012
This paper seeks to collect as many Welsh lake legends as possible, to produce a thematic classification and to analyse each resultant category and subcategory from a historical point of view.
Fernandez, Carles-Enric
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The Perception of Ancestral History, Legends, and Myths of the Alorese Muslim Minority Group in East Nusa Tenggara, Indonesia

IBDA': Jurnal Kebudayaan Islam
This paper comprehensively examines the perception of the Alorese about their ancestral history, legends, and myths. It describes the Alorese people's minority status, traces their ancestral lineage, explains the interaction dynamics between coastal and
Yunus Sulistyono, Laili Etika Rahmawati, Ismail Tamal Biat, Rika Febrianti, Muhammad Zafar, Niken Aprilyana   +5 more
doaj   +1 more source