Results 91 to 100 of about 18,113 (230)

Legionnaires’ Disease: Clinicoradiological Comparison of Sporadic Versus Outbreak Cases

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2017
Background: In 2015, New York City experienced the worst outbreak of Legionnaires’ disease in the history of the city. We compare patients seen during the 2015 outbreak with sporadic cases of Legionella during the past 5 years.
Hafiz Rizwan Talib Hashmi, Lakshmi Saladi, Frances Petersen, Misbahuddin Khaja, Gilda Diaz-Fuentes   +4 more
doaj   +1 more source

JAK Inhibitors for Treatment of VEXAS Syndrome: A Systematic Review of 186 Cases

Dermatology Research and Practice, Volume 2025, Issue 1, 2025.
Objectives: Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic (VEXAS) syndrome is an autoinflammatory disease with a wide spectrum of manifestations and no standard treatment. Janus kinase inhibitors (JAK‐I) are small‐molecule drugs that affect many molecular pathways.
Saeed Bahramian, Patrick Fazeli, Arezou Rafati, Sardar Demokri, Huria Memari, Amirali Soheili, Farzad Esmaeili, Mohammad Pourmehdi Ardebili, Haniye Erfani, Seyed Mohammad Vahabi, Ioannis D. Bassukas   +10 more
wiley   +1 more source

Risk management of water systems in residential homes : The ‘process’ of Legionella prevention [PDF]

, 2017
In the present study data was collect and analysed to gain evidence for the present situation of Legionella risk management and prevention of water systems in different buildings in the Canton of Zurich, Switzerland.
Füchslin, Hans Peter, Hofer, Susanne, Keserue, Hans Anton, Leiblein, Thomas W., Tucker, Matthew   +4 more
core   +1 more source

Unraveling the Genetic Predisposition on Respiratory Infections: From Single Nucleotide Polymorphisms to Inborn Errors of Immunity

Interdisciplinary Perspectives on Infectious Diseases, Volume 2025, Issue 1, 2025.
Background: The complex interplay between the human genome and microbial pathogens has captured scientific interest, leading to profound insights into the genetic basis of host’s susceptibility to infections. Objective: Here, we explore the spectrum of genetic susceptibility in infectious diseases, ranging from common single nucleotide polymorphisms ...
Francesca Conti, Mattia Moratti, Bianca Laura Cinicola, Riccardo Castagnoli, Riccardo Papa, Silvia Federici, Giuliana Giardino, Lucia Leonardi, Maria Sangerardi, Annarosa Soresina, Gian Luigi Marseglia, Michele Miraglia Del Giudice, Marcello Lanari, Caterina Cancrini, Vassilios Lougaris, Fabio Cardinale, on behalf of the Immunology Committee of the Italian Society of Pediatric Allergology and Immunology (SIAIP), Suraiya Saleem   +17 more
wiley   +1 more source

A RARE CASE OF RHABDOMYOLYSIS AND ANURIC RENAL FAILURE IN A PATIENT WITH LEGIONNAIRES' DISEASE [PDF]

, 2020
Robert E. Rudd, Alivia Adkins, Muthiah Muthiah   +2 more
openalex   +1 more source

Microbial Dynamics and Quality Monitoring in Biopharmaceutical Production

ChemBioEng Reviews, Volume 11, Issue 6, December 2024.
This review evaluates current methods for bioprocessing of non‐mammalian cells for biopharmaceuticals synthesis. Advanced technology and standardized testing are needed to improve production, reduce costs, prevent contamination, and enhance supply availability.
Rosha Pashang, Kimberley A. Gilbride, Jannis Wenk   +2 more
wiley   +1 more source

A CASE OF LEGIONNAIRES' DISEASE IN 70-YEAR-OLD PATIENT: DELAYED DIAGNOSIS AFTER EXPOSURE TO CONTAMINATED HOTEL SHOWER [PDF]

Journal of IMAB
Legionellosis, an acute infectious disease, often manifests as Legionnaires' disease with severe pneumonia. Transmission occurs via inhalation of Legionella-contaminated aerosols generated by contaminated water systems, with increased susceptibility in ...
Viktoriya Trendafilova, Velina Stoeva, Ivan Baltadzhiev   +2 more
doaj   +1 more source

Intra-species and inter-kingdom signaling of Legionella pneumophila [PDF]

, 2017
The ubiquitous Gram-negative bacterium Legionella pneumophila parasitizes environ mental amoebae and, upon inhalation, replicates in alveolar macrophages, thus causing a life-threatening pneumonia called "Legionnaires' disease." The opportunistic ...
Hilbi, Hubert, Hochstrasser, Ramon
core   +2 more sources

Probe‐capture targeted next‐generation sequencing: A novel approach for pathogen and antimicrobial resistance detection in sepsis

Clinical and Translational Discovery, Volume 5, Issue 4, August 2025.
Chitra Ravi, Adam D. Irwin, Patrick N. A. Harris   +2 more
wiley   +1 more source

Using mathematical modeling to study the dynamics of Legionnaires' disease and consider management options

Mathematical Biosciences and Engineering
Legionnaires' disease (LD) is a largely understudied and underreported pneumonic environmentally transmitted disease caused by the bacteria Legionella. It primarily occurs in places with poorly maintained artificial sources of water. There is currently a
Mark Z. Wang, Christina J. Edholm, Lihong Zhao   +2 more
doaj   +1 more source