Results 41 to 50 of about 4,848,364 (170)
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.Legionella pneumophila infection leads to the release of pathogen‐associated molecular patterns, which recruits the adaptor protein MYD88, initiating both activating (e.g., NF‐κB) and inhibitory (e.g., PI3K/AKT) signaling pathways that regulate IL‐12 gene expression.
Kara Vasilew +12 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, Volume 600, Issue 11, Page 1589-1604, June 2026.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Legionnaires’ Disease Outbreaks and Cooling Towers, New York City, New York, USA
Emerging Infectious Diseases, 2017 The incidence of Legionnaires’ disease in the United States has been increasing since 2000. Outbreaks and clusters are associated with decorative, recreational, domestic, and industrial water systems, with the largest outbreaks being caused by cooling ...
Robert Fitzhenry +15 more
doaj +1 more source
MicrobiologyOpen, Volume 15, Issue 3, June 2026.Legionella pneumophila is the principal species responsible for Legionnaires' disease, and measuring microbial load is fundamental to the analysis of environmental water samples. This study compared a new lipopolysaccharide bioprobe method (Microcolony Counter Analysis), which detects and counts L.
Savina Ditommaso +6 more
wiley +1 more source
Hospital Acquired Infection and Legionnaires' Disease [PDF]
, 2020 More than 10,000 patients are hospitalized every year with Legionnaires' disease in the United States alone. Legionnaires' disease is also an important public health topic as it involves environmental and public issues, as far as its spread and ...
core +1 more source
A community outbreak of Legionnaires’ disease caused by outdoor hot tubs for private use in a hotel
Frontiers in Microbiology, 2023 During the period October–November 2017, an outbreak of Legionnaires’ disease involving 27 cases occurred in the tourist area of Palmanova (Mallorca, Spain).
Mercedes Gumá +9 more
doaj +1 more source
Nanobodies: A Promising Toolkit for Diagnostic Applications
SmartMat, Volume 7, Issue 3, June 2026.This review focuses on camelid‐derived nanobodies (VHHs) and explains how their small size and high stability support robust diagnostic design. Applications across ELISA, lateral flow assays, and PET/SPECT imaging are summarized, along with clinical progress such as caplacizumab.
Wei Wu +11 more
wiley +1 more source
Legionnaires’ Disease Incidence and Risk Factors, New York, New York, USA, 2002–2011
Emerging Infectious Diseases, 2014 Incidence of Legionnaires’ disease in the United States is increasing. We reviewed case records to determine the the epidemiology of and risk factors for the 1,449 cases reported to the New York City Department of Health and Mental Hygiene, New York, New
Andrea Farnham +3 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Germline GATA2 deficiency predisposes to bone marrow failure, myeloid neoplasia, and immune dysregulation. The syndrome is often complicated by infection with intracellular pathogens and viruses, autoimmunity, and inflammation. Hemophagocytic lymphohistiocytosis (HLH) is a rare occurrence that can present further management challenges.
Harry Wilson +3 more
wiley +1 more source
Is a Proactive Approach to Controlling Legionella in the Environment Justified?
Food Technology and Biotechnology, 2021 Research background. Legionella are Gram-negative bacteria that are ubiquitous in the natural environment. Contaminated water in man-made water systems is a potential source of transmission of legionnaires’ disease.
Daniela Glažar Ivče +9 more
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