A Reflective Verbalization Strategy to Trigger Alternative Diagnostic Hypotheses
ABSTRACT Rationale Physicians sometimes encounter various types of gut feelings (GFs) during clinical diagnosis. The type of GF addressed in this paper refers to the intuitive sense that the generated hypothesis might be incorrect. An appropriate diagnosis cannot be obtained unless these GFs are articulated and inventive solutions are devised.
Sho Isoda +5 more
wiley +1 more source
Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors. [PDF]
We have examined receptors mediating phagocytosis of the intracellular bacterial pathogen, Legionella pneumophila. Three mAbs against the type 3 complement receptor (CR3), which recognizes C3bi, inhibit adherence of L.
Horwitz, MA, Payne, NR
core
Prevalence study of . contamination in ferries and cruise ships [PDF]
Background In the last years, international traffic volume has significantly increased, raising the risk for acquisition of infectious diseases. Among travel-associated infections, increased incidence of legionellosis has been reported among travellers ...
Masia Maria +7 more
core +1 more source
Global use of Haemophilus influenzae type b conjugate vaccine.
Haemophilus influenzae type b (Hib) conjugate vaccines have been underutilized globally. We report progress in global use of Hib vaccines included in national immunization schedules.
Bear, Allyson P +9 more
core +1 more source
Seasonal Host Shifts for Legionella Within an Industrial Water‐Cooling System
Taxonomic profiling for Legionella (the causative agent of Legionnaires' disease) and protist hosts within a water cooling tower showed seasonal peaks for Legionella that were associated with taxonomic shifts in the protist community. Legionella frequency was tracked using amplicon sequencing (blue line) and serogroup profiling (red line).
Suzanne Crull +8 more
wiley +1 more source
Legionella pneumophila modulates the host cytoskeleton by an effector of transglutaminase activity
Abstract The bacterial pathogen Legionella pneumophila delivers more than 330 effector proteins into host cells through its Dot/Icm type IV secretion system (T4SS) to facilitate its intracellular replication. A number of these effectors modulate organelle trafficking pathways to create a membrane‐bound niche called the Legionella‐containing vacuole ...
Yan Liu, Yao Liu, Zhao‐Qing Luo
wiley +1 more source
Webster\u27s Third and the 20th Century [PDF]
To what extent can year dates be found in Webster\u27s Third? Year dates are scattered throughout Webster\u27s Third, in definitions and in etymologies, ranging from many thousands of years BC to the very recent. Here\u27s a slimmed-down version of the
Francis, Darryl
core +1 more source
Evaluation of the national surveillance of Legionnaires' disease in Norway, 2008-2017
Background In Norway, Legionnaires’ disease is reportable upon clinical suspicion to public health authorities and mandatorily notifiable through the Norwegian surveillance system for communicable diseases (MSIS) for both clinicians and laboratories.
Cecilia Wolff +4 more
doaj +1 more source
Legionella causes 2–15% of community acquired pneumonia cases that require hospitalization and it is the second most common cause of serious pneumonia that needs admission in an intensive care unit.
Aayesha J. Soni, Alan Peter
doaj +1 more source
Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin [PDF]
International audienceThe human pathogen Legionella pneumophila must evade host cell death signaling to enable replication in lung macrophages and to cause disease. After bacterial growth, however, L.
Abraham, Gilu +10 more
core +4 more sources

