Results 31 to 40 of about 2,240 (260)

L'exécution de Suréna: Les Tendances Dans Les Relations de Pouvoir Chez Les Parthes

open access: yesBanber Arevelagitut'yan Instituti
Le capitaine Parthe Suréna, victorieux des légions de Crassus fut exécuté par Orodès aussitôt après sa victoire éclatante. L'examen de ce fait portent à révéler les particularité du développement politique de l'Empire Parthe.
Rouben Manasserian
doaj   +6 more sources

Le nombre, l’identité et l’origine des légions du Bellum Africum

open access: yesNuova Antologia Militare
A review of the literature on Caesar’s campaigns reveals that specialists offer differing estimates of the number of Caesarian legions involved in the African War. Some count ten legions, while others propose twelve.
Batiste Gérardin
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Gdyby Legiony nie powstały…

open access: yesDzieje Najnowsze, 2017
Przedmiotem rozważań jest wpływ walk Legionów Polskich na wydarzenia, które podczas I wojny światowej wyniosły sprawę Polski na arenę międzynarodową i stworzyły warunki sprzyjające formowaniu Błękitnej Armii, a także próba sformułowania odpowiedzi na ...
Janusz Odziemkowski
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The “Legiony” (Legions) Project. On Henryk Sienkiewicz’s final novel

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2019
The archived rough draft of Legiony, the last novel by Henryk Sienkiewicz, contains 139 separate pages, including drafts of textual varieties, subsequent variants, and the printed version. The diverse material and the remaining writer’s notes enabled the
Agnieszka Kuniczuk-Trzcinowicz
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Genomic and immune profiling of pre-invasive lung adenocarcinoma

open access: yesNature Communications, 2019
The genomic and immune landscape of pre-invasive lung adenocarcinoma is poorly understood. Here, the authors perform exome and transcriptome sequencing on precursor legions and invasive lung adenocarcinomas, identifying recurrently mutated genes in pre ...
Haiquan Chen   +39 more
doaj   +1 more source

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