Results 41 to 50 of about 394,046 (321)
Bayesian spatial voting model to characterize the legislative behavior of the Colombian Senate 2010-2014 [PDF]
arXiv, 2021 This paper applies Bayesian methodologies to characterize the legislative behavior of the Colombian Senate during the period 2010-2014. The analysis is carried out through the plenary roll call votes of this legislative chamber. In addition, parliamentary electoral behavior is operationalized by implementing the one-dimensional standard Bayesian ideal ...
arxiv
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Workplace Breastfeeding Legislation and Female Labor Force Participation in the United States [PDF]
arXiv, 2022 This paper studies the effects of legislation mandating the provision of workplace breastfeeding amenities on the labor force participation of women in the United States. Using both the American Community Survey and the Panel Study of Income Dynamics, in a staggered difference-in-differences framework, I find evidence that workplace breastfeeding ...
arxiv
Molecular Oncology, EarlyView.Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Network Analysis in the Legal Domain: A complex model for European Union legal sources [PDF]
, 2015 Legislators, designers of legal information systems, as well as citizens face often problems due to the interdependence of the laws and the growing number of references needed to interpret them. Quantifying this complexity is not an easy task. In this paper, we introduce the "Legislation Network" as a novel approach to address related problems. We have
arxiv +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
White Christian Nationalism in the Rural United States
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Many scholars have sought to link the rise of right‐wing populist movements, like White Christian Nationalism (WCN), to the impacts of political‐economic structural changes, such as globalization and financialization. Although these structural changes may explain some grievances, they do not explain why people express those grievances in the ...
Leland L. Glenna
wiley +1 more source
Crime Against History: Slavery, Race, and the 1776 Report
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT With the 2025 executive order, “Ending Radical Indoctrination in K‐12 Schooling,” the Trump administration reestablished the 1776 Commission, which produced The 1776 Report. This article argues that this report, which is an unsubtle response to The 1619 Project, reveals how White Christian Nationalists wish to mandate that a hyper‐patriotic ...
William V. Trollinger
wiley +1 more source
White Christian Nationalism: Adult Education and Threats to Democracy
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Adult education has a historical and ongoing commitment to fostering democratic relationships, demonstrated by the tendency of adult education to be called upon when social change and realignment are most desirable. This article considers the philosophical and pragmatic possibilities for adult education at this moment, when White Christian ...
Ralf St. Clair, Lyn Tett, Rob Black
wiley +1 more source