How do primary care consultation dynamics affect the timeliness of cancer diagnosis in people with one or more long-term conditions? A qualitative study. [PDF]
Valasaki M +9 more
europepmc +1 more source
Public real estate in transition : The quest for efficiency, flexibility and legitimacy
Cor van Montfort, Claudia Noort-Verhoeff
openalex +1 more source
In Response: Effectively addressing bias in risk assessment will require attention both to the nature of scientific objectivity and to public perceptions of research legitimacy—A perspective from academia [PDF]
Kevin C. Elliott
openalex +1 more source
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Eco-Anxiety in Higher Education Professionals: Psychological Impacts, Institutional Trust, and Policy Implications. [PDF]
Steele SL.
europepmc +1 more source
Unpaired Learning‐Enabled Nanotube Identification from AFM Images
Identifying nanotubes on rough substrates is notoriously challenging for conventional image analysis. This work presents an unpaired deep learning approach that automatically extracts nanotube networks from atomic force microscopy images, even on complex polymeric surfaces used in roll‐to‐roll printing.
Soyoung Na +10 more
wiley +1 more source
Constructing and contesting industry's role in multistakeholder governance: a qualitative analysis of responses to WHO consultations. [PDF]
van den Akker A +4 more
europepmc +1 more source
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia +14 more
wiley +1 more source
Strategic decoupling through legitimacy: the sustainability-innovation gap in the food processing sector and its health implications. [PDF]
Yucel M.
europepmc +1 more source

