Results 91 to 100 of about 52,437 (276)

Abnormal β‐Hydroxybutyrylation Modification of ARG1 Drives Reprogramming of Arginine Metabolism to Promote the Progression of Colorectal Cancer

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
Alterations in arginine metabolism and β‐hydroxybutyrylation (Kbhb) modifications play a critical role in tumor progression. This study reveals valuable insights into arginine metabolism reprogramming involving the ARG1‐Kbhb/P300/SLC3A2 signaling axis and uncovers an effective therapy combining BHB with ARG1 inhibitor through conventional enzymatic and
Chuman Lin   +6 more
wiley   +1 more source

SARC018_SPORE02: Phase II Study of Mocetinostat Administered with Gemcitabine for Patients with Metastatic Leiomyosarcoma with Progression or Relapse following Prior Treatment with Gemcitabine-Containing Therapy

open access: yesSarcoma, 2018
Histone deacetylase inhibitors (HDACi) can reverse chemoresistance, enhance chemotherapy-induced cytotoxicity, and reduce sarcoma proliferation in cell lines and animal models.
E. Choy   +10 more
semanticscholar   +1 more source

An Unusual Presentation of Metastatic Soft Tissue Sarcoma to the Left Atrium and Pulmonary Veins: A Case Report and Comprehensive Literature Review

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
A summary of the patient's history and treatment process. ABSTRACT Metastatic soft tissue sarcoma (STS) is a rare and aggressive malignancy arising from connective tissues. It is characterized by its ability to metastasize to distant sites, with the lungs being the most common location. Despite advances in diagnosis and treatment, the prognosis remains
Abdulhamid Bagheri   +7 more
wiley   +1 more source

Rare Surgical Management of Renal Lymphangiectasia: Marsupialization Into Peritoneal Cavity

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Renal lymphangiectasia is a rare condition resulting from miscommunication between renal and retroperitoneal lymphatic ducts, causing ductal dilatation and lymphatic fluid collection. In this report, we present this condition and highlight an uncommon management approach involving cyst marsupialization.
Ibrahim Barghouth   +4 more
wiley   +1 more source

Primary Leiomyosarcoma of the Male Breast: A Case Report

open access: yesCase Reports in Medicine, 2010
Primary leiomyosarcoma of the breast is a rare tumour with only around thirty cases reported in the literature. Most of the cases reported are in females, while only a few are reported in males.
Yazan Masannat   +2 more
doaj   +1 more source

A Massive Interstitial Cervical Leiomyoma Successfully Treated With Myomectomy: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Cervical leiomyomas are rare pelvic tumors, with interstitial subtypes being the least common. This case highlights a 44‐year‐old female with a 14‐mm interstitial cervical leiomyoma, successfully treated with myomectomy. This approach preserved fertility, demonstrating its feasibility as an alternative to hysterectomy for select patients.
Marah Mansour   +6 more
wiley   +1 more source

Leiomyosarcoma of tongue

open access: yesCHRISMED Journal of Health and Research, 2014
Leiomyosarcoma is a malignant smooth muscle tumour. Oral leiomyosarcoma in particular of the tongue is extremely rare and poorly documented. We report a case of 38 year old woman with 1 year history of painless growing mass on the left hemi tongue with ...
S V Dhanasekaran   +2 more
doaj   +1 more source

The prevalence of occult leiomyosarcoma at surgery for presumed uterine fibroids: a meta-analysis

open access: yesGynecological Surgery, 2015
There is a concern regarding the risk of occult leiomyosarcomas found at surgery for presumed benign fibroids. We sought to produce a comprehensive review of published data addressing this issue and provide high-quality prevalence estimates for clinical ...
E. Pritts   +6 more
semanticscholar   +1 more source

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