Summary Patients with relapsed or refractory acute myeloid leukaemia (r/r AML) harbouring FMS‐like tyrosine kinase 3 (FLT3) mutations generally have poor prognosis and limited treatment options. The second‐generation FLT3 inhibitor gilteritinib provides better disease control compared to standard relapse therapies and was approved based on two ...
Desiree Kunadt +55 more
wiley +1 more source
Culture-specific transcriptional drifts limit the fidelity of organoid infection models. [PDF]
Schweizer PE +20 more
europepmc +1 more source
The optimal stent‐strategy in paediatric pyeloplasty: a systematic review and network meta‐analysis
Objectives To compare internal JJ stenting, external transanastomotic stenting and stentless repair after Anderson–Hynes pyeloplasty in children. Patients and Methods A systematic review and network meta‐analysis of children with pelvi‐ureteric junction (PUJ) obstruction undergoing Anderson‐Hynes pyeloplasty.
Ophelia Aubert +10 more
wiley +1 more source
The economic impact of clinical pharmacists in a tertiary care centre in Germany: pharmacoeconomic benefit calculation using cost-avoidance analysis. [PDF]
Borella J +5 more
europepmc +1 more source
A tutorial for understanding SEM using R: Where do all the numbers come from?
Abstract Structural equation modeling (SEM) is often seen as a complex and difficult method, especially for those who want to understand how the numbers in SEM software output are actually computed. Although many open‐source SEM tools are now available—especially in the R programming environment—looking into their source code to understand the ...
Yves Rosseel, Marc Vidal
wiley +1 more source
Remote assessment of caries, MIH, and plaque on intraoral 3D scan images: Findings from the LIFE Child study. [PDF]
Stiller N +8 more
europepmc +1 more source
Idiographic interrater reliability measures for intensive longitudinal multirater data
Abstract Interrater reliability plays a crucial role in various areas of psychology. In this article, we propose a multilevel latent time series model for intensive longitudinal data with structurally different raters (e.g., self‐reports and partner reports).
Tobias Koch +4 more
wiley +1 more source
Fasting ghrelin as mediator between obesity and depressive symptoms: a pre-registered study. [PDF]
Endres KJ +8 more
europepmc +1 more source
The characteristics of settlement of Neanderthals in northern Central Europe during the earlier phases of the Middle Palaeolithic (Marine Isotope Stage 8–6) have been a matter of debate for decades, specifically regarding the population dynamics at such latitudes during the coldest phases. In this paper, we review the known archaeological record of the
Gianpiero Di Maida +5 more
wiley +1 more source
Disseminated angiostrongylosis with involvement of the central nervous system as a cause of sudden death in a dog in Germany. [PDF]
Dembowski M +5 more
europepmc +1 more source

