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In vitro activity of cinnamaldehyde on Leishmania (Leishmania) amazonensis
Experimental Parasitology, 2022Tegumentary leishmaniasis is an endemic disease that urgently needs new and effective treatments. L. amazonensis is one of the main species involved in the transmission of this infectious and non-contagious disease. The currently available treatments for leishmaniasis have high toxicity and vary in efficacy.
Aline Ávila Brustolin +5 more
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2013
The presence of different sets of several enzymes that participate in the Krebs-Henseleit cycle has been used to identify several genera of trypanosomatids. One of these enzymes is arginase (L-arginine amidinohydrolase, E.C. 3.5.3.1), a metalloenzyme that catalyzes the hydrolysis of L-arginine to L-ornithine and urea.
Maria Fernanda Laranjeira da Silva +1 more
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The presence of different sets of several enzymes that participate in the Krebs-Henseleit cycle has been used to identify several genera of trypanosomatids. One of these enzymes is arginase (L-arginine amidinohydrolase, E.C. 3.5.3.1), a metalloenzyme that catalyzes the hydrolysis of L-arginine to L-ornithine and urea.
Maria Fernanda Laranjeira da Silva +1 more
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Characterization of Leishmania (Leishmania) tropica axenic amastigotes
Acta Tropica, 2010Optimum conditions for generating Leishmania (Leishmania) tropica axenic amastigotes (AxA) in culture were determined, pH 5.5/36 degrees C, and the parasites characterized by different techniques, including light microscopy, macrophage infection, stage specific antigen expression and differential display. AxA were morphologically similar to amastigotes
Gabriele Schönian +3 more
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Proteophosphoglycans of Leishmania
Parasitology Today, 2000Proteophosphoglycans are an expanding family of highly glycosylated Leishmania proteins with many unusual and some unique structural features. The novel protein-glycan linkage in proteophosphoglycans - phosphoglycosylation of Ser by lipophosphoglycan-like structures - emerges as a major form of protein glycosylation in Leishmania.
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Leishmania (Leishmania) chagasi is not vertically transmitted in dogs
Veterinary Parasitology, 2002The most frequent and most important mode of human or canine visceral leishmaniasis (CVL) transmission is through the bite of infected sand flies. This study investigates Leishmania (Leishmania) chagasi vertical transmission in offspring of naturally infected dogs. Thus 63 puppies from 18 female dogs with CVL were used.
Wagner Luiz Tafuri +6 more
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Leishmania RNA Viruses in Leishmania of the Viannia Subgenus
The American Journal of Tropical Medicine and Hygiene, 1996Karyotype analysis of 69 strains of Leishmania belonging to three species of the Viannia subgenus originating from the southeastern and southwestern regions of Colombia revealed approximately 5.3-kb RNAs in four strains of L. braziliensis and also in the World Health Organization reference strain L. guyanensis IWHI/BR/78/M5313.
Nancy G. Saravia +3 more
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Purine metabolism in Leishmania donovani and Leishmania braziliensis
Biochimica et Biophysica Acta (BBA) - General Subjects, 1978We have studied purine metabolism in the culture forms of Leishmania donovani and Leishmania braziliensis. These organisms are incapable of synthesizing purines de novo from glycine, serine, or formate and require an exogenous purine for growth. This requirement is better satisfied by adenosine or hypoxanthine than by guanosine.
Randolph L. Berens +2 more
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Veterinary Parasitology, 2007
Leishmania parasites cause a group of diseases collectively known as leishmaniases. The primary hosts of Leishmania are sylvatic mammals of several orders (Rodentia, Marsupialia, Carnivora, etc.). Under certain circumstances, particularly in peridomestic and domestic transmission foci, synanthropic and domestic animals can act as source of infection ...
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Leishmania parasites cause a group of diseases collectively known as leishmaniases. The primary hosts of Leishmania are sylvatic mammals of several orders (Rodentia, Marsupialia, Carnivora, etc.). Under certain circumstances, particularly in peridomestic and domestic transmission foci, synanthropic and domestic animals can act as source of infection ...
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Biochemical characterization of serine transport in Leishmania (Leishmania) amazonensis
Molecular and Biochemical Parasitology, 2009In addition to its role as a protein component in Leishmania, serine is also a precursor for the synthesis of both phosphatidylserine, which is a membrane molecule involved in parasite invasion and inactivation of macrophages, and sphingolipids, which are necessary for Leishmania to differentiate into its infective forms.
Ricardo Andrade Zampieri +5 more
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The subgenus Leishmania (Leishmania): a citation correction
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2000Ralph Lainson, Jeffrey Jon Shaw
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