Results 131 to 140 of about 885 (162)
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Parasite Immunology, 2021
Abstract In some central‐American countries, Leishmania ( L .) infantum chagasi infection can cause non‐ulcerated or atypical cutaneous leishmaniasis (NUCL) in addition to the classic clinical ...
Márcia Dalastra Laurenti +8 more
openaire +2 more sources
Abstract In some central‐American countries, Leishmania ( L .) infantum chagasi infection can cause non‐ulcerated or atypical cutaneous leishmaniasis (NUCL) in addition to the classic clinical ...
Márcia Dalastra Laurenti +8 more
openaire +2 more sources
Acta Tropica, 2016
The most commonly used drugs against visceral leishmaniasis are based on pentavalent antimonial compounds, which have played a fundamental role in therapy for over 70 years. However, the treatment is painful and has severe toxic side effects that can be fatal. Antimonial resistance is spreading and reaching alarming proportions.
Fernando L, Dutra +6 more
openaire +4 more sources
The most commonly used drugs against visceral leishmaniasis are based on pentavalent antimonial compounds, which have played a fundamental role in therapy for over 70 years. However, the treatment is painful and has severe toxic side effects that can be fatal. Antimonial resistance is spreading and reaching alarming proportions.
Fernando L, Dutra +6 more
openaire +4 more sources
Importance of worldwide asymptomatic carriers of Leishmania infantum (L. chagasi) in human
Acta Tropica, 2011Leishmaniasis due to Leishmania infantum (syn. L. chagasi) infection is a zoonotic disease present mainly in Mediterranean basin, central Asia and Brazil. Besides a limited number of human cases of clinical visceral leishmaniasis, a great number of infections remains asymptomatic. In this review, the prevalence of asymptomatic carriers of L.
Grégory, Michel +3 more
openaire +2 more sources
Parasite Immunology, 2020
Abstract Skin lesions in nonulcerated cutaneous leishmaniasis (NUCL) caused by Leishmania (L.) infantum chagasi are characterized by a mononuclear inflammatory infiltrate in the dermis, which is composed mainly of lymphocytes, followed by macrophages, few plasma cells and ...
Gabriela Venicia Araujo Flores +6 more
openaire +2 more sources
Abstract Skin lesions in nonulcerated cutaneous leishmaniasis (NUCL) caused by Leishmania (L.) infantum chagasi are characterized by a mononuclear inflammatory infiltrate in the dermis, which is composed mainly of lymphocytes, followed by macrophages, few plasma cells and ...
Gabriela Venicia Araujo Flores +6 more
openaire +2 more sources
The Veterinary Journal, 2014
Canine leishmaniosis caused by Leishmania infantum is still a common disease in endemic areas, such as the Mediterranean countries, and has progressively expanded into non-endemic areas like Central and Northern Europe. The aim of this article is to critically review current knowledge on the diagnosis and treatment of this disease. In dogs with typical
Chiara, Noli +1 more
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Canine leishmaniosis caused by Leishmania infantum is still a common disease in endemic areas, such as the Mediterranean countries, and has progressively expanded into non-endemic areas like Central and Northern Europe. The aim of this article is to critically review current knowledge on the diagnosis and treatment of this disease. In dogs with typical
Chiara, Noli +1 more
openaire +2 more sources
Molecular and Cellular Biochemistry, 2013
Drug repositioning has been considered a promising approach to discover novel treatments against neglected diseases. Among the major protozoan diseases, leishmaniasis remains a public health threat with few therapeutic alternatives, affecting 12 million people in 98 countries.
Juliana Tonini, Mesquita +3 more
openaire +2 more sources
Drug repositioning has been considered a promising approach to discover novel treatments against neglected diseases. Among the major protozoan diseases, leishmaniasis remains a public health threat with few therapeutic alternatives, affecting 12 million people in 98 countries.
Juliana Tonini, Mesquita +3 more
openaire +2 more sources
Parasitology International, 2021
The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infections in the Brazilian Amazon has been defined using DTH/IFAT-IgG immune assays and the clinical statuses of infected individuals, revealing five profiles: three asymptomatic [Asymptomatic Infection (AI), Subclinical Resistant Infection (SRI), and Indeterminate Initial ...
Patrícia Karla Santos, Ramos +7 more
openaire +2 more sources
The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infections in the Brazilian Amazon has been defined using DTH/IFAT-IgG immune assays and the clinical statuses of infected individuals, revealing five profiles: three asymptomatic [Asymptomatic Infection (AI), Subclinical Resistant Infection (SRI), and Indeterminate Initial ...
Patrícia Karla Santos, Ramos +7 more
openaire +2 more sources
Parasitology Research, 2009
This was a prospective study carried out during a period over 2 years (May/2006-September/2008) with a cohort of 1,099 individuals of both genders, aged 1 year old and older, from an endemic area of American visceral leishmaniasis (AVL) in Pará state, Brazil.
Fernando Tobias, Silveira +9 more
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This was a prospective study carried out during a period over 2 years (May/2006-September/2008) with a cohort of 1,099 individuals of both genders, aged 1 year old and older, from an endemic area of American visceral leishmaniasis (AVL) in Pará state, Brazil.
Fernando Tobias, Silveira +9 more
openaire +2 more sources
Parasitology International, 2023
In Central America, Leishmania (L.) infantum chagasi infection causes visceral leishmaniasis (VL) and non-ulcerated cutaneous leishmaniasis (NUCL). The aim of the present study was to evaluate the course of an experimental infection in hamsters caused by L.
Gabriela V, Araujo Flores +10 more
openaire +2 more sources
In Central America, Leishmania (L.) infantum chagasi infection causes visceral leishmaniasis (VL) and non-ulcerated cutaneous leishmaniasis (NUCL). The aim of the present study was to evaluate the course of an experimental infection in hamsters caused by L.
Gabriela V, Araujo Flores +10 more
openaire +2 more sources
Transactions of the Royal Society of Tropical Medicine and Hygiene
Abstract Background In Honduras, Central America, human infection with Leishmania (L.) infantum chagasi can lead to the clinical manifestation known as non-ulcerated cutaneous leishmaniasis (NUCL) and visceral leishmaniasis. This study evaluates the dynamics of human infection with L.
Wilfredo Sosa-Ochoa +6 more
openaire +2 more sources
Abstract Background In Honduras, Central America, human infection with Leishmania (L.) infantum chagasi can lead to the clinical manifestation known as non-ulcerated cutaneous leishmaniasis (NUCL) and visceral leishmaniasis. This study evaluates the dynamics of human infection with L.
Wilfredo Sosa-Ochoa +6 more
openaire +2 more sources