Effective Genome Editing in Leishmania (Viannia) braziliensis Stably Expressing Cas9 and T7 RNA Polymerase [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Until 2015, loss-of-function studies to elucidate protein function in Leishmania relied on gene disruption through homologous recombination. Then, the CRISPR/Cas9 revolution reached these protozoan parasites allowing efficient genome editing with one ...
Caroline R. Espada +12 more
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Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition [PDF]
Frontiers in Microbiology, 2017 Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis.
Erica V. De Castro Levatti +7 more
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Leishmania (Viannia) braziliensis growth in vitro culture relies more on folic acid availability than Leihsmania (Leishmania) amazonensis [PDF]
Memorias do Instituto Oswaldo Cruz, 2005 We compared the in vitro growth of promastigotes from two Leishmania species in TC-100 and Schneider media. Leishmania (Leishmania) amazonensis replication rates were similar in both tissue culture media and reached maximum rates by 48 h.
Andrea Niño, Marcela Camacho
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Leishmania (Viannia) braziliensis type 2 as probable etiological agent of canine cutaneous leishmaniasis in Brazilian Amazon. [PDF]
PLoS ONE, 2019 Canine cutaneous leishmaniasis (CCL) is a zoonosis of public health interest, and in the Americas, Leishmania (Viannia) braziliensis has been identified as the main etiological agent. The present study sought to investigate Leishmania spp.
Andreia Fernandes Brilhante +11 more
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Personal experience with diagnostic and therapeutic aspects of human Leishmania (Viannia) braziliensis in Três Braços [PDF]
Memorias do Instituto Oswaldo Cruz, 1994 Diagnostic and therapeutic aspects of human infection with Leishmania (Viannia) braziliensis found in the littoral forest of the state of Bahia are reviewed. There is pressing need for alternative cheap oral drug therapy.
Philip D. Marsden
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Leishmania (Viannia) braziliensis em cães naturalmente infectados Leishmania (Viannia) braziliensis in naturally infected dogs [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2003 Foram estudados oito cães provenientes do Município de Maricá (RJ), com lesões sugestivas de leishmaniose tegumentar americana por métodos parasitológicos e sorológicos. Leishmania spp foi encontrada em seis cães através do cultivo in vitro.
Maria de Fátima Madeira +6 more
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Revista do Instituto de Medicina Tropical de São Paulo, 2002 The current article reports the case of a 19-month-old-girl, from the state of Minas Gerais, Brazil, with visceral leishmaniasis, by Leishmania (Viannia) braziliensis, and Human Immunodeficiency Virus (HIV) co-infection.
SILVA Eduardo Sérgio da +4 more
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Intranasal vaccination with leishmanial antigens protects golden hamsters (Mesocricetus auratus) against Leishmania (Viannia) Braziliensis infection. [PDF]
PLoS Neglected Tropical Diseases, 2015 Previous results have shown that oral and intranasal administration of particulate Leishmania (Leishmania) amazonensis antigens (LaAg) partially protects mice against L. amazonensis infection.
Luzinei da Silva-Couto +8 more
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Revista Peruana de Medicina Experimental y Salud Pública, 1999 Se elaboró extractos de antígenos solubles de Leishmania (leishmanina), a partir de formas promastigotes de Leishmania (Viannia) peruviana y Leishmania (Viannia) braziliensis.
G Minaya +5 more
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Central and Effector Memory Human CD4+ and CD8+ T Cells During Cutaneous Leishmaniasis and After in Vitro Stimulation With Leishmania (Viannia) Braziliensis Epitopes [PDF]
Vaccines, 2023 Rafael de Freitas e Silva +2 more
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