Results 61 to 70 of about 20,249 (182)

Acrodermatitis Dysmetabolica as a Cutaneous Manifestation of Isoleucine Deficiency in Maple Syrup Urine Disease: A Systematic Review of Reported Cases

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aim Maple Syrup Urine Disease (MSUD) is a metabolic disorder affecting branched‐chain amino acid metabolism. While neurological symptoms are well‐characterized, cutaneous manifestations such as acrodermatitis dysmetabolica (AD) caused by isoleucine deficiency remain underrecognized.
Bahareh Abtahi‐naeini   +4 more
wiley   +1 more source

Biological Evaluation, Molecular Docking, MD Simulation Study and Synthesis of (Z)‐N’‐(3‐phenoxybenzylidene)‐2‐(substituted‐amino aryl) Acetohydrazid

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Synthesis and biological evaluation (antibacterial, antifungal, anti‐tuberculosis, antiprotozoal) and in silico molecular docking of biphenyl ether based Schiff's base analogues. ABSTRACT In order to investigate their possible biological activity, a number of new Schiff base compounds based on diaryl ether, specifically 2‐(substituted‐arylamino)‐N′‐(3 ...
Navin B. Patel   +7 more
wiley   +1 more source

Coumarin‐Benzimidazole Hybrids as Multitarget Scaffolds for Antileishmanial Drug Discovery

open access: yesChemistrySelect, Volume 11, Issue 38, 13 October 2026.
Coumarin‐benzimidazole hybrids emerge as promising antileishmanial agents through virtual screening against essential Leishmania enzymes, Cathepsin B (CatB), and N‐myristoyltransferase (NMT). Molecular docking and dynamics simulations reveal highly stable target interactions that surpass the reference drug miltefosine (MTF).
Fernanda Melo Jucá   +4 more
wiley   +1 more source

Synthesis, Anti‐Leishmania amazonensis Activity, Cytotoxicity, and Molecular Docking of Anthranilate–Naphthoquinone Hybrids

open access: yesChemistrySelect, Volume 11, Issue 40, 27 October 2026.
New anthranilate–naphthoquinone hybrids display potent inhibition of Leishmania (L.) amazonensis with low host cell toxicity. Molecular docking reveals key interactions with TR, GP63, and PTR1, suggesting a multitarget mechanism that contributes to parasite death.
Eduardo Miranda da Silva Magesfeste   +7 more
wiley   +1 more source

Mini-Exon Genotyping of Leishmania Species in Khuzestan Province, Southwest Iran [PDF]

open access: yesIranian Journal of Parasitology, 2010
Background: Leishmaniasis is a protozoan disease cause by Leishmania genus. Anthroponotic and zoono­tic cutaneous leishmaniasis are endemic in Iran. The aim of this study was to identify the causative agent of cutaneous leishmaniasis by mini-exon gene in
J Saki   +7 more
doaj   +1 more source

Symmetrical Cutaneous Leishmaniasis

open access: yesActa Dermato-Venereologica, 2005
Sir, Cutaneous leishmaniasis (CL) is a protozoan disease present in Old and New Worlds (1, 2). It is endemic in the Mediterranian basin, particularly in the rural areas of Sicily where almost 60% of Italian cases occur. The disease is caused by parasites of the genus Leishmania infantum, carried by specific species of sandflies as Phlebotomus ...
GUARNERI, Claudio   +1 more
openaire   +2 more sources

A Declining Trend of 'Leishmaniasis' Based on Previous Data in Larstan, South of Iran 2007–2017

open access: yesAnnals of Global Health, 2019
Introduction: 'Cutaneous Leishmaniasis' is a unicellular of the Leishmania type, and 0.7 to 1.2 million people are annually infected by 'Cutaneous Leishmaniasis'. Larestan is one of the southern cities of Fars Province.
Ahmad Abolghazi   +4 more
doaj   +1 more source

Dermatologic Manifestations in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis

open access: yesActa Medica Iranica, 2019
The human T cell lymphotropic virus type-1 (HTLV-1) is associated with adult T cell leukemia/lymphoma (ATL) and other disorders, including a slowly progressive demyelinating paraparesis, known as HTLV-1-associated myelopathy/tropical spastic paraparesis (
Reza Boostani   +8 more
doaj  

Cutaneous leishmaniasis in Iraq

open access: yesThe Journal of Infection in Developing Countries, 2009
To determine the incidence ofcutaneous leishmaniasis (CL) in Alhaweja District and to clarify the secondary bacterial infection inCL.A prospective survey was performed in the outpatient clinic of Alhaweja General Hospital. All the patients who presented at the dermatology clinic during the period from 1 October 2004 to the end of April 2005 were ...
Abdulghani Mohamad AlSamarai   +1 more
openaire   +4 more sources

Rifampicin in Cutaneous Leishmaniasis

open access: yesJournal of International Medical Research, 1978
A study is described which aimed at assessing the efficacy of rifampicin in the treatment of cutaneous leishmaniasis. A total of thirteen patients suffering from this condition were admitted to the study and were given rifampicin 600 mg daily. Three patients dropped out due to reasons unconnected with the trial and one patient left when the lesions ...
openaire   +2 more sources

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