Results 61 to 70 of about 44,611 (218)

Human myiasis in Ecuador. [PDF]

open access: yes, 2020
We review epidemiological and clinical data on human myiasis from Ecuador, based on data from the Ministry of Public Health (MPH) and a review of the available literature for clinical cases.
Calvopina, M   +5 more
core   +1 more source

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study

open access: yesChemMedChem, Volume 21, Issue 7, 14 April 2026.
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe   +6 more
wiley   +1 more source

Household knowledge, practice and treatment seeking behaviors towards cutaneous leishmaniasis in the endemic rural communities of Ganta- afeshum district, Tigrai, northern Ethiopia, 2019: a cross-sectional study

open access: yesTropical Diseases, Travel Medicine and Vaccines, 2021
Background Cutaneous leishmaniasis is endemic to Ethiopia. However, the prevention and control efforts of leishmaniasis remain unfocused with clear knowledge and practice gaps within the country.
Kebede Tesfay   +9 more
doaj   +1 more source

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. [PDF]

open access: yes, 1994
Leishmania major are intramacrophage parasites whose eradication requires the induction of T helper 1 (Th1) effector cells capable of activating macrophages to a microbicidal state.
Locksley, RM   +4 more
core   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1087-1097, April 2026.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon   +12 more
wiley   +1 more source

A National Survey: Desire of Dermatology Residents to Train in Cosmetic Dermatology and Its Association With Learning Medical Dermatology

open access: yesActa Medica Iranica, 2018
The main challenge for training in cosmetic dermatology is the difference in the attitudes of residency programs and residents about the necessity and amount of education during the residency period.
Bita Kiafar   +6 more
doaj  

Local therapies in cutaneous leishmaniasis: a review study

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2020
Old World cutaneous leishmaniasis (OWCL) is a relatively common parasitic infection that is among endemic diseases in many regions worldwide, particularly in Iran. Leishmania major and Leishmania tropica species with over 500,000 and 400,000 annual cases
Sadegh Vahabi-Amlashi   +2 more
doaj  

Emerging and Re-Emerging Zoonoses of Dogs and Cats. [PDF]

open access: yes, 2014
Since the middle of the 20th century, pets are more frequently considered as "family members" within households. However, cats and dogs still can be a source of human infection by various zoonotic pathogens.
Chomel, Bruno B
core   +2 more sources

American Cutaneous Leishmaniasis

open access: yesArchives of Pathology & Laboratory Medicine, 2002
Abstract We present 3 cases of American cutaneous leishmaniasis occurring in soldiers of a unit of US Army Rangers who parachuted into the jungles of Panama. Shortly after returning to the United States, these 3 soldiers each developed a crusted, indurated papule, which slowly enlarged during the following 6 weeks.
M A J Michael, Royer, C O L Mark, Crowe
openaire   +2 more sources

Using Q-methodology to understand the perspectives and practical experiences of dermatologists about treatment difficulties of cutaneous leishmaniasis

open access: yesBMC Infectious Diseases, 2020
Background During the outbreak of cutaneous leishmaniasis in the Kurdistan Region of Iraq that started in 2015, the course of the disease and the treatment were not consistent with the available literature.
Dindar S. Qurtas, Nazar Pauls Shabila
doaj   +1 more source

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