Results 61 to 70 of about 9,597 (197)

Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues   +6 more
wiley   +1 more source

Review and new therapeutic alternatives for the treatment of cutaneous Leishmaniasis [PDF]

open access: yes, 2014
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704Leishmaniasis comprises a group of diseases caused by protozoa of the genus Leishmania and has two basic clinical forms, visceral Leishmaniasis and cutaneous Leishmaniasis. The clinical
Pujol Brugués, Alba   +1 more
core  

The Safety and Efficacy of an Immunomodulator Garlic‐Based Cream (LeishG1) for Treating Uncomplicated Cutaneous Leishmaniasis: A Single‐Blind, Multi‐Center Study

open access: yesHealth Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) is a major problem in developing nations, particularly in the Middle East. Novel herbal treatment options may provide a safe alternative associated with favorable outcomes in CL lesion healing.
Fatemeh Emadi   +8 more
wiley   +1 more source

Progress of Mucocutaneous Leishmaniasis to Drug Nonresponsive Diffuse Cutaneous Leishmaniasis in Ethiopia. A Case Report

open access: yesInternational Medical Case Reports Journal, 2020
Banchamlak Tegegne,1 Getaneh Alemu2 1Amhara Public Health Institute, Bahir Dar, Ethiopia; 2Department of Medical Laboratory Science, Bahir Dar University, Bahir Dar, EthiopiaCorrespondence: Getaneh Alemu PO Box 79 Tel +251922842776Email getanehmlt@gmail ...
Tegegne B, Alemu G
doaj  

Cheilitis: An unusual presentation of Mucocutaneous Leishmaniasis

open access: yesClinical Case Reports, 2018
Key Clinical Message The Mucocutaneous Leishmaniasis (MCL) involving lip is extremely uncommon. A clinical diagnosis of Leishmaniasis of the lips is often challenging to the treating clinician and may result in delayed diagnosis as this case illustrates.
Vathulan Sujanitha   +3 more
doaj   +1 more source

Leishmaniasis: Recent epidemiological studies in the Middle East

open access: yesFrontiers in Microbiology, 2023
Leishmaniasis, one of the most neglected tropical diseases (NTDs), is the third most important vector-borne disease worldwide. This disease has a global impact and severity of the infection and is greatest in the Middle East.
Chinyere A. Knight   +5 more
doaj   +1 more source

Testing of four Leishmania vaccine candidates in a mouse model of infection with Leishmania (Viannia) braziliensis, the main causative agent of cutaneous leishmaniasis in the new world [PDF]

open access: yes, 2007
We evaluated whether four recombinant antigens previously used for vaccination against experimental infection with Leishmania (Leishmania) major could also induce protective immunity against a challenge with Leishmania (Viannia) braziliensis, the species
Ba Brazil   +8 more
core   +3 more sources

Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines

open access: yeseJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer   +6 more
wiley   +1 more source

Кожный лейшманиоз: этиология, клиника, диагностика, лечение [PDF]

open access: yes, 2016
КОЖНЫЕ БОЛЕЗНИПАРАЗИТАРНЫЕ БОЛЕЗНИПРОТОЗОЙНЫЕ ИНФЕКЦИИЛЕЙШМАНИОЗ /ДИАГН /ТЕР /ЭТИОЛПАРОМОМИЦИНАЗОЛЫСТИБОГЛЮКОНАТ НАТРИЯДЕРМАТОСКОПИЯЛЕКАРСТВЕННАЯ ...
Адаскевич, В. П.   +2 more
core  

Mitochondrial Dysfunction Induced by a Novel Salicylate‐Based 1,2,3‐Triazole Salt With Potent Antileishmanial Activity

open access: yesChemical Biology &Drug Design, Volume 106, Issue 6, December 2025.
A novel salicylate‐based 1,2,3‐triazole salt was synthesized and demonstrated potent and selective activity against Leishmania amazonensis. The most active compound induced mitochondrial dysfunction without hemolytic effects. In silico analyses also suggested favorable pharmacokinetic properties and oral bioavailability.
Bruno A. De Oliveira   +8 more
wiley   +1 more source

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