Results 121 to 130 of about 37,430 (216)

Successful Bailout Retrieval of an Active‐Fixation Atrial Leadless Pacemaker Following Suspected Tissue Entrapment During Repositioning

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
(A) Unscrewing of AVEIR AR. (B) After unscrewing, the device appeared to be trapped with the stretched helix. (C) Successful retrieval was achieved by fully covering the device. (D) The retrieved device demonstrated the stretched helix. ABSTRACT An 81‐year‐old woman with a medical history of mechanical mitral valve replacement, Maze procedure, and ...
Toshiya Yoshida, Akira Kasagawa, Daisuke Togashi, Ikutaro Nakajima, Tomoo Harada   +4 more
wiley   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

The Role of the Antidepressants in Managing Chemotherapy‐Induced Neuropathic Pain: A Systematic Review

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From symptom relief to multimodal care: duloxetine and amitriptyline may reduce established CIPN‐related pain and provide a therapeutic foundation for future combination strategies. ABSTRACT Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and debilitating complication of cancer treatment, characterized by neuropathic pain, sensory ...
Rosamaria Caminiti, Valeria Mazza, Saverio Nucera, Francesca Oppedisano, Lucia Carmela Passacatini, Jessica Maiuolo, Valentina Malafoglia, Alessandro Giorgio, Andrea Soluri, Claudia Pileggi, Carlo Tomino, Vincenzo Mollace, Sara Ilari, Carolina Muscoli   +13 more
wiley   +1 more source

Lenalidomide for the treatment of relapsed and refractory multiple myeloma

Cancer Management and Research, 2012
Niels WCJ van de Donk,1,2 Güllü Görgün,1 Richard WJ Groen,1,3 Jana Jakubikova,1 Constantine S Mitsiades,1 Teru Hideshima,1 Jacob Laubach,1 Inger S Nijhof,2 Reinier A Raymakers,2 Henk M Lokhorst,2 Paul G Richardson,1 ...
van de Donk NW, Görgün G, Groen RW, Jakubikova J, Mitsiades CS, Hideshima T, Laubach J, Nijhof IS, Raymakers RA, Lokhorst HM, Richardson PG, Anderson KC   +11 more
doaj  

To Treat or Not to Treat: Navigating Early‐Stage CLL in the Era of Targeted Therapy

European Journal of Haematology, Volume 117, Issue 4, Page 750-766, October 2026.
ABSTRACT Chronic lymphocytic leukemia (CLL) is most frequently diagnosed at early, asymptomatic stages (Rai 0/Binet A), in which a watch‐and‐wait strategy remains the standard of care, based on historical trials demonstrating no overall survival benefit from early treatment.
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Giovanna Cutrona, Antonella Bruzzese, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Nicola Amodio, Franco Fais, Antonino Neri, Manlio Ferrarini, Valter Gattei, Fortunato Morabito, Massimo Gentile   +16 more
wiley   +1 more source

Lenalidomide-Induced Acute Interstitial Nephritis

, 2010
The first case of biopsy-proven lenalidomide-induced acute interstitial nephritis is presented.
Danniele G. Holanda, Evan J. Lipson, Michael A. McDevitt, Derek M. Fine, Carol Ann Huff   +4 more
core   +1 more source

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

European Journal of Haematology, Volume 117, Issue 4, Page 849-863, October 2026.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi, Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +15 more
wiley   +1 more source

Therapeutic Benefits of Lenalidomide in Hematological Malignancies

, 2019
Lenalidomide is an immunomodulatory agent, which has action against most of the hematological malignancies. Apart from its immunomodulation, it has other properties such as antiproliferation and antiangiogenesis.
Durai Mavalavan Vasudevan Manimoliyan, Mohammed Shafi Abdulsalam   +1 more
core   +1 more source

Longitudinal assessments of MRD in high‐risk newly diagnosed transplant‐ineligible multiple myeloma in the BENEFIT study (IFM2020‐05)

HemaSphere, Volume 10, Issue 10, October 2026.
Jill Corre, Jerome Lambert, Arthur Bobin, Salomon Manier, Aurore Perrot, Lionel Karlin, Murielle Roussel, Noemie Bigot, Omar Benbrahim, Olivier Allangba, Philippe Rey, Véronique Dorvaux, Marguerite Vignon, Virginie Roland, Réda Garidi, Jean‐Noel Bastie, Marie‐Lorraine Chretien, Sophie Godet, Lydia Montes, Brieuc Cherel, Anne Vekhoff, Thomas Chalopin, Borhane Slama, Kamel Laribi, Claire Dingremont, Christophe Roul, Valentine Richez‐Olivier, Clara Mariette, Sophie Rigaudeau, Claire Calmettes, Mamoun Dib, Mourad Tiab, Laure Vincent, Jacques Delaunay, Sabrina Maheo, Anais Schavgoulidze, Laurent Frenzel, Pascal Godmer, Ronan Le Calloch, Emilie Chalayer, Helene Gardeney, Margaret Macro, Bruno Royer, Stephanie Harel, Olivier Decaux, Bertrand Arnulf, Karim Belhadj, Aurelie Gontier, Cyrille Touzeau, Mohamad Mohty, Philippe Moreau, Thierry Facon, Cyrille Hulin, Xavier Leleu   +53 more
wiley   +1 more source

Clinical management of clonal hematopoiesis

Cancer, Volume 132, Issue 18, 15 September 2026.
ABSTRACT Clonal hematopoiesis, particularly clonal hematopoiesis of indeterminate potential and clonal cytopenia of undetermined significance, is an age‐related premalignant condition characterized by the expansion of hematopoietic clones carrying somatic mutations.
Kelly S. Chien, Guillermo Garcia‐Manero   +1 more
wiley   +1 more source