Results 31 to 40 of about 8,367 (262)

The Tolstoy-Dolan Mission and the Establishment of US-Tibetan Relations: An investigation into the events that unfolded after the first visit of American representatives to Lhasa in 1943 [PDF]

open access: yes, 2017
This article investigates the events that unfolded during and after the visit of two Office of Strategic Service (OSS) agents to Lhasa in spring 1943.
Ernst, Maximilian
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Driving safety: enhancing communication between clients, constructors and designers [PDF]

open access: yes, 2008
This paper, which stems from qualitative research undertaken by the CRC for Construction Innovation in the context of the development of a Guide to Best Practice for Safer Construction in the Australian construction industry, investigates the ...
Brown, Kerry   +3 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Diplomatic activities of M.M. Litvinov in the USA during the Great Patriotic War (1941–1943)

open access: yesВестник Московского Университета. Серия XXV: Международные отношения и мировая политика
The Great Patriotic War is one of the highlights in the history of Soviet-American cooperation. The USSR and the United States managed to overcome the inertia of mutual mistrust that persisted throughout most of the interwarperiod, taking together the ...
A. A. Vershinin, P. A. Tupikin
doaj   +1 more source

Improving the mechanical recycling and reuse of mixed plastics and polymer composites [PDF]

open access: yes, 2009
This is a post-print version of the chapter.In this chapter we will explore the possibilities and viability of commercially recycling and reusing of composites and mixed polymer based waste that is difficult and expensive to separate into individual ...
Tarverdi, K
core  

What is event led regeneration? Are we confusing terminology or will London 2012 be the first Games to truly benefit the local existing population? [PDF]

open access: yes, 2010
The term regeneration means keeping the locality available for the same social classes and improving the infrastructure for their benefit, however examination of previous games including Barcelona 1992 and Sydney 2000 has shown evidence of renaissance ...
Sadd, Deborah
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

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