Results 61 to 70 of about 1,280,703 (249)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Length-weight and length-length relationships for six fish species from Zohreh River, Iran

open access: yesInternational Journal of Aquatic Biology, 2017
The present study reports Length-weight and length-length parameters for six fish species belonging to four families from the Zohreh River. The weight-length relationships were estimated using the equation W= 𝛼Lb.
Yazdan Keivany, Mazaher Zamani-Faradonbe
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Length-Weight Relationships, Maturity, and Reproductive Season of the Fringelip Mullet Crenimugil crenilabis (Forsskål, 1775) from the Arabian Sea Coast of Oman

open access: yesJournal of Agricultural and Marine Sciences, 2008
Fringelip mullet (Crenimugil crenilabis) caught at Al Duqum and Salalah in the Arabian  Sea region of Omanwere sampled monthly between January 2001 and December 2002.
Abdullah Al-Nahdi   +3 more
doaj   +1 more source

Length-weight relationships of Hyperopisus bebe occidentalis in Zaria Dam [PDF]

open access: yes, 2013
The morphometric parameters of 54 Hyperopisus hebe occidentalis obtained from Zaria Dam were investigated. The length occidentalis examined ranged from 18.9-41.0 cm and weight ranged from 25-425g, the largest male weighed 175g while the female was 425g ...
Abubakar, Y., Adeyemi, O., Onimisi, H.U.
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Studies on length-weight and length-length relationships of a catfish Eutropiichthyes vacha Hamilton (Schilbeidae: Silurifo)

open access: yesCaspian Journal of Environmental Sciences, 2007
Present study describes the length-weight (LWR) and length-length (LLR) relationships of a freshwater catfish Eutropiichthyes vacha Hamilton from Indus River, Sindh, Pakistan. A total of 281 specimen of E. vacha were collected from fisherman?s catch from
Soomro, A.N.   +3 more
doaj  

Length, Weight, and Yield in Channel Catfish, Lake Diane, MI [PDF]

open access: yes, 2011
Background: Channel catfish (Ictalurus punctatus) are important to both commercial aquaculture and recreational fisheries. Little published data is available on length-weight relationships of channel catfish in Michigan.
Ashley Crowe   +3 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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