Results 101 to 110 of about 883,300 (305)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Length-weight and length-length relationships of three fish species from the Heihe River, northwest China [PDF]

, 2018
Length-weight (LWRs) and length-length (LLRs) relationships are reported for three fish species belonging to two families and two genera from the Heihe River, northwest China.
Wei, J., Huang, D., Chen, J., Lei, H., Chen, F., Chang, X., Zhang, Z., Fang, Y.   +7 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Length-weight relationships of commercially important marine fishes and shellfishes of the southern coast of Karnataka, India [PDF]

The parameters of the length-weight relationship of the form W = aLb are presented for 51 species of commercially important marine fishes and shellfishes caught along the southern coast of Karnataka, India.
Mohamed, K.S., Abdulrahiman, K.P., Harishnayak, T., Zacharia, P.U.   +3 more
core  

Establishing a weight-length baseline for evaluating changes in yellowfin tuna (Thunnus albacores) body condition in the Western Indian Ocean [PDF]

, 2013
Standard weight (Ws) equations were established for yellowfin tuna (Thunnus albacares) in the Western Indian Ocean and used as a baseline for calculating relative weight (Wr) indices.
Harikishun, Ameil
core  

Association of day length and weather conditions with physical activity levels in older community dwelling people [PDF]

, 2014
Background: Weather is a potentially important determinant of physical activity. Little work has been done examining the relationship between weather and physical activity, and potential modifiers of any relationship in older people. Wetherefore examined
McMurdo, Marion E. T., Falko F Sniehotta, Donnan, Peter T, Vadiveloo, Thenmalar, Miles D Witham, Crombie, Iain K, Witham, Miles D, Crombie, Iain K., McMurdo Marion E. T., Witham, Miles D., Donnan Peter T., Vadiveloo Thenmalar, Sniehotta Falko F., Sniehotta, Falko F., Donnan, Peter T.; id_orcid, Feng Zhiqiang, McMurdo, Marion E T, Iain K Crombie, Peter T Donnan, Crombie Iain K., Marion E T McMurdo, Thenmalar Vadiveloo, Feng, Zhiqiang, Sniehotta, Falko F, Zhiqiang Feng, Witham Miles D.   +25 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

THE CONDITION OF FISH FROM SOME FRESHWATERS OF CROATIA [PDF]

Croatian Journal of Fisheries, 2007
The 41 »bases for fishery management« and 16 related studies were thoroughly analyzed. The data on 39 species, registered in 1 to 23 Croatian water bodies were statistically processed for CF and length–weight relationship parameters. The great variations
Tomislav Treer, Marina Piria, Nikica Šprem, Z. Prpa   +3 more
doaj