Results 61 to 70 of about 392,967 (304)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Body weight-length relationships in giant otters (Pteronura brasiliensis) (Carnivora, Mustelidae)

Brazilian Archives of Biology and Technology, 2009
Few giant otters (Pteronura brasiliensis) have been measured and weighed and its actual size is controversial in the literature. This study presents the weight-length relationship of Amazonian giant otters using 15 captive individuals. The maximum length
Fernando César Weber Rosas, Carla Soares da Rocha, Gália Ely de Mattos, Stella Maris Lazzarini   +3 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Length-weight relationships of seven cyprinid fish species from the Kaptai Lake, Bangladesh

, 2020
Length-weight relationships of seven cyprinid fish species from the Kaptai Lake ...
MA Hanif (17202520), MM Ali (9852968), Shoaib M Siddik (15905075)   +2 more
core   +1 more source

Length-length and Length-weight Relationships in Astacus leptodactylus in Bandar Anzali Region

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 1997
Different length - weight relationship in 1000 male and 201 female of freshwater crayfish were studied and it was revealed that the length - length relationship is best described through linear regression, while weight - length relation is best described
Sh. Baradaran noveiri
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Length-weight relationships for Sardinella maderensis in Senegalese waters.

, 2016
Blue triangles and red dots represent the length-weight relationships during the cold season and hot season, respectively. The black line is the model fitted to all measurements regardless of season.
Alioune Faye (2825966), Kamarel Ba (2825948), Najih Lazar (2825972), Alassane Sarr (2825951), Jacques Panfili (2825960), Oumar Sadio (2825963), Omar Thiom Thiaw (335361), Modou Thiaw (2825975), Timothée Brochier (2825969), Patrice Brehmer (2825954), Ismaïla Ndiaye (2825957)   +10 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Composition and length-weight relationships of fish species in Lake Erhai, southwestern China

, 2013
Length-weight relationships (LWRs) are described for 23 fish species (five indigenous species and 18 exotic species) in Lake Erhai, a plateau deep lake located in southwestern China.
Li, ZJ (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, 7 Donghu South Rd, Wuhan 430072, Hubei Province, Peoples R China., Liu, J. S., Zhu, F. Y., Ye, S. W., Guo, Z. Q., Zhang, T. L., Li, Z. J., Tang, J. F.   +7 more
core   +1 more source

Length-Weight Relationships for Thirty Fish Species in Lake Niushan, a Shallow Macrophytic Yangtze Lake in Chin

Asian Fisheries Science, 2007
Length-weight relationships are presented for 30 fish species captured from April 2002 to January 2004 in Lake Niushan, China. The values of the exponent b in the length-weight relationships (W=aLb) ranged from 2.845 to 3.435 and the median of b was 3 ...
S. YE, Z. LI, G. FENG, W. CAO
doaj   +1 more source