Results 251 to 260 of about 421,254 (307)

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

Effect of Prehabilitation on the 6-Minute Walk Test and Length of Hospital Stay in Frail Older People: A Meta-Analysis of Randomized Controlled Trials. [PDF]

open access: yesInt J Environ Res Public Health
López-González M   +5 more
europepmc   +1 more source

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