Results 161 to 170 of about 539,038 (312)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
پیاورد سلامت, 2017 Background and Aim: Hospitals should be able to satisfy their clients’ needs in less time and with best quality possible. Length of Stay (LOS) in hospitals is considered as a key performance indicator, especially in emergency departments.
Hamed Basir Ghafouri +4 more
doaj
, 2013 Glenn Magee,1 Art Zbrozek21Premier Research Services, Charlotte, NC, USA; 2CSL Behring, King of Prussia, PA, USABackground: Fluid overload, including transfusion-associated circulatory overload (TACO), is a serious complication of fresh frozen plasma ...
Zbrozek A, Magee G
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Impact of intravenous thrombolysis on length of hospital stay in cases of acute ischemic stroke
, 2018 Narongrit Kasemsap,1,2 Nisa Vorasoot,1,2 Kannikar Kongbunkiat,1,2 Udomlack Peansukwech,1 Somsak Tiamkao,1,2 Kittisak Sawanyawisuth1,3,4 1Department of Medicine, Faculty of Medicine, 2North-Eastern Stroke Research Group, 3Research Center in Back, Neck ...
Peansukwech U +5 more
core
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
, 2009 [[abstract]]A good prediction model of length of stay for stroke patients in rehabilitation ward can be used as the basis of reimbursement for stroke rehabilitation in global budget and case payment system .
Chien-Lin Lin
core
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source