Results 61 to 70 of about 9,473,405 (304)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Length-weight and length-length relationships, Relative condition factor and Fulton’s condition factor of Five Cyprinid species in Anzali wetland, southwest of the Caspian Sea

open access: yesCaspian Journal of Environmental Sciences, 2012
This study was conducted to determine length-weight and length-length relationships, relative condition factor (Krel) and Fulton’s condition factor (K) for five species including Scardinius erythrophtalmus, Carassius auratus gibelio, Cyprinus carpio ...
Moradinasab, Gh.   +4 more
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Spatial and temporal variation in population structure of Hemigrammus marginatus (Characiformes: Characidae) in streams of the Ivinhema River Basin, Brazil

open access: yesZoologia (Curitiba), 2012
The present study has assessed spatial and temporal variations in the length structure of Hemigrammus marginatus Ellis, 1911 and estimated growth parameters for the species.
Luzia da Silva Lourenço   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Estimation of length weight relationship in fishes [PDF]

open access: yes, 2017
Organisms generally increase in size (length, weight) during development. The key factors that influence the growth of fish are the quantity of food available, the number of fish utilizing same food source, temperature, oxygen and other water quality ...
Kuriakose, Somy
core   +1 more source

ICHTHYOFAUNA OF THE LOWER PART OF BLIZNEC STREAM [PDF]

open access: yesCroatian Journal of Fisheries, 2009
The fish were sampled in the lower parts of the Bliznec stream using an electroaggregate on two separate occasions in November 2008. A total of 50 fish were sampled.
Marina Piria   +10 more
doaj  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Length-weight relationship, length-length relationship and condition factor of some fish populations in Büyükçekmece Reservoir (İstanbul, Turkey)

open access: yesJournal of Limnology and Freshwater Fisheries Research, 2016
In present study, length-weight relationship, length-length relationship and condition factor values were calculated for 11 freshwater fish species of Buyukcekmece Reservoir. Fish specimens were collected by gillnets having different mesh size between March 2009 and February 2010, monthly.
SAÇ, Gülşah, OKGERMAN, Hacer
openaire   +2 more sources

Home - About - Disclaimer - Privacy