Results 41 to 50 of about 10,843 (238)

Neuropathic Pain and Enlarged Nerves in Adult Noonan Syndrome and Noonan Syndrome With Multiple Lentigines: Health‐Related Quality of Life and Neurologic Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan syndrome (NS) and the clinically related Noonan syndrome with multiple lentigines (NSML) belong to the group of RASopathies. Although pain is not mentioned as a characteristic feature, it has recently been reported as a clinically significant problem.
Jos M. T. Draaisma, Wesley Reintjes, Erika Leenders, Fieke Draaisma, Melanie Burgers, Lotte Kleimeier, Marco Tartaglia, Merel Klaassens, Ruud Becks, Steven Renes, Ellen Wingbermühle, Nicol C. Voermans, Nens van Alfen   +12 more
wiley   +1 more source

Radiotherapy for lentigo maligna and lentigo maligna melanoma – a systematic review

Radiation Oncology, 2020
Lentigo maligna (LM) is the most common subtype of in situ melanoma und occurs frequently in the sun-exposed head and neck region in elderly patients. The therapeutic “gold standard” is surgical excision, as there is the risk of progression to invasive ...
Alexandra Hendrickx, Antonio Cozzio, Ludwig Plasswilm, Cédric M. Panje   +3 more
doaj   +1 more source

Senile Lentigo – Cosmetic or Medical Issue of the Elderly Population [PDF]

, 2010
Senile lentigo or age spots are hyperpigmented macules of skin that occur in irregular shapes, appearing most commonly in the sun- exposed areas of the skin such as on the face and back of the hands. Senile lentigo is a common component of photoaged skin
Marija Buljan, Mirna Šitum, V. Šitum, Vedrana Bulat, Zvonimir Puljiz, Željana Bolanča   +5 more
core   +1 more source

The HAM10000 dataset, a large collection of multi-source dermatoscopic images of common pigmented skin lesions

, 2018
Training of neural networks for automated diagnosis of pigmented skin lesions is hampered by the small size and lack of diversity of available datasets of dermatoscopic images. We tackle this problem by releasing the HAM10000 ("Human Against Machine with
Kittler, Harald, Rosendahl, Cliff, Tschandl, Philipp   +2 more
core   +1 more source

Identification of Predictive Factors for Isolated Brain Progression in Patients With Cerebral Metastatic Melanoma After Treatment With Stereotactic Brain Radiotherapy

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Melanomas often metastasize to the brain, leading to a significantly poor prognosis despite advances in local and systemic treatments. In clinical practice, we frequently observe varying response patterns and progression dynamics between cerebral and extra cerebral sites. Objectives This study aims to identify predictive factors for
Manuel Croix, Justine Lequesne, Julien Geffrelot, Anne Dompmartin, Jean Matthieu L'orphelin   +4 more
wiley   +1 more source

Reduced Visibility of Pigment Network Under Sub‐UV Reflectance Dermatoscopy Compared to Polarised Dermatoscopy: A Novel Diagnostic Clue to Differentiate Melanomas From Nevi

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Melanoma accounts for more than 75% of skin cancer‐related mortality. Dermatoscopy is an evidence‐based technique for earlier detection, yet differentiating melanocytic lesions remains challenging. Sub‐UV reflectance dermatoscopy (sUVRD) uses purple light (405 nm) to visualise chromophore distribution in the skin.
L. Dupont, P. Pietkiewicz, J. Anriot, P. Greco, A. Petiot‐Walch, C. Coste, E. Aurambout, S. Darnis, M. Amini‐Adle, L. Thomas   +9 more
wiley   +1 more source

Efficacy and safety of long-pulse pulsed dye laser delivered with compression versus cryotherapy for treatment of solar lentigines

Indian Journal of Dermatology, 2011
Background: Although cryotherapy is still the first-line therapy for solar lentigines, because of the side effects such as post-inflammatory hyperpigmentation (PIH), especially in patients with darker skin types, pigment-specific lasers should be ...
Hassan Seirafi, Soheil Fateh, Farshad Farnaghi, Amir H Ehsani, Pedram Noormohammadpour   +4 more
doaj   +1 more source

Three roots of melanoma [PDF]

, 2008
Segura et al1 describe morphologic features of melanomas with a nodular component using in vivo reflectance-mode confocal microscopy (RCM) and correlate these RCM findings with histopathologic findings.
Argenziano, G., Ferrara, G., Hofmann-Wellenhof, R., Leinweber, B., Marghoob, A. A., Pellacani, G., Scope, A., Soyer, H. P., Zalaudek, I.   +8 more
core   +1 more source

Clinical and Histopathological Assessment of the Field of Cancerization in Human Skin Before and After Treatment With a 1927‐nm Thulium Fractional Laser

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Field cancerization is a major concern in photodamaged skin due to its risk of progression to squamous cell carcinoma. The 1927‐nm thulium laser has emerged as a promising therapy, but its isolated effects on this condition remain underexplored.
Livia Maria Oliveira Salviano, André Bubna Hirayama, Marcella Soares Pincelli, Vivian Nunes Arruda, Rodrigo Cesar Davanço, Luiza Reis Pinto, Luis Antonio Ribeiro Torezan   +6 more
wiley   +1 more source

Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports [PDF]

, 2014
Ipilimumab is a monoclonal antibody that blocks cytotoxic T-lymphocyte antigen4 (CTLA-4), an inhibitory molecule typically expressed on T cells. Blockade of CTLA-4 induces an overall activation of T cells, including an immune-mediated anti-tumour ...
Brochez, Lieve, Cocquyt, Veronique, KRUSE, VIBEKE, Marlier, Joke, Van Belle, Simon   +4 more
core   +2 more sources