Results 1 to 10 of about 89 (87)
Lentes intraoculares acomodativas
, 2022 La presbicia, signo inequívoco del envejecimiento, sigue siendo «una enfermedad sin tratamiento universal, que sin duda tiene muchos tratamientos». Presenta múltiples intentos de abordaje realizados por la oftalmología hasta la fecha. En una disciplina donde los resultados son cada vez más precisos, los oftalmólogos, y los cirujanos refractivos en ...
Peris Martínez, Cristina +7 more
openaire +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Caracterización óptica de lentes intraoculares = Optical characterization of intraocular lenses
, 2023 The optical characterization of an intraocular lens (IOL) provides objective and quantitative information that is essential to fully understand its performance as an implant that replaces the crystalline lens in the human visual system. Additionally, it can be used to predict the performance of the new IOL designs. This thesis analyses the main sources
openaire +4 more sources
Twelve‐Month Real‐World Outcomes of Faricimab for Treatment‐Naive Neovascular AMD in Australia
Clinical &Experimental Ophthalmology, Volume 54, Issue 4, Page 500-506, May/June 2026.ABSTRACT Background To provide insights into the effectiveness and safety of faricimab for treatment‐naïve eyes with neovascular age‐related macular degeneration (nAMD). Methods A retrospective cohort study using a prospectively‐designed registry. Treatment‐naïve eyes with nAMD in Australia starting treatment with faricimab between Jan 2023–Sep 2024 ...
Mark Gillies +8 more
wiley +1 more source
NMR in Biomedicine, Volume 39, Issue 3, March 2026.Retinal metabolic changes were analyzed using proton magnetic resonance spectroscopy (1H‐MRS), marking an initial application of this non‐invasive method on living eyes. Key metabolites were identified within the retinal region of adult rats. The observed changes following intense blue light exposure were predominantly attributable to the retina, as it
Lacramioara Samoila +10 more
wiley +1 more source
Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips
Advanced Biology, Volume 10, Issue 2, February 2026.Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck +4 more
wiley +1 more source
Nanobiotechnology‐Based Approaches for Uveal Melanoma Treatment
SmartMat, Volume 7, Issue 1, February 2026.Emerging platforms for uveal melanoma combine precision drug delivery, ROS‐amplifying modalities, and nucleic acid transport to overcome ocular barriers and immunosuppressive niches. Targeted nanoparticles, virus‐like constructs, and injectable depots enable localized activation, controlled release, and gene‐level reprogramming.
Nadezhda A. Pechnikova +8 more
wiley +1 more source
Cardiovascular response to altered gravity in healthy adults: Insight from graded tilt testing
Physiological Reports, Volume 14, Issue 4, February 2026.Abstract Microgravity exposure during spaceflight induces a thoracocephalic fluid shift that affects the cardiovascular system both during flight and after return to Earth. As the proportion of female astronauts increases, it is essential to understand how altered gravity impacts cardiovascular function across sexes.
Adrien Robin +2 more
wiley +1 more source
Journal of Ophthalmology, Volume 2026, Issue 1, 2026.Myopia has emerged as a major global public health concern. Atropine, recognized as one of the foremost interventions for myopia control, has been validated for its efficacy and safety through a multitude of clinical studies. This article examines the most recent advancements in understanding atropine’s mechanisms of action, optimizing dosage ...
Qinling Jiang +4 more
wiley +1 more source
Integrative cardiovascular dose–response to graded lower‐body negative pressure
Experimental Physiology, Volume 110, Issue 12, Page 1852-1879, December 1, 2025.ABSTRACT Lower‐body negative pressure (LBNP) has been posited as a potential spaceflight countermeasure to counteract the physiological deconditioning related to fluid shifts in microgravity. However, open questions remain regarding the magnitude of LBNP that should be applied.
Richard S. Whittle +5 more
wiley +1 more source