Report of two cases of lepromatous leprosy at an early age
International Journal of Infectious Diseases, 2020 Leprosy is an infectious disease that has a broad spectrum of clinical manifestations. Lepromatous leprosy has a deficient cellular immune response and high bacillary multiplication.
Gabriela Belmonte Dorilêo +3 more
doaj +1 more source
Journal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.ABSTRACT Mycobacterium fortuitum mycobacteremia and arthritis were diagnosed in a Briard dog from northern California. The dog was evaluated for lameness and had a history of immunosuppressive treatment and splenectomy for refractory immune thrombocytopenia.
Tianjiao Li +5 more
wiley +1 more source
Evidencing leprosy neuronal inflammation by 18-Fluoro-deoxy-glucose.
PLoS Neglected Tropical Diseases, 2023 BackgroundLeprosy is caused by multiple interactions between Mycobacterium leprae (M. leprae) and the host's peripheral nerve cells. M. leprae primarily invades Schwann cells, causing nerve damage and consequent development of disabilities.
Patricia Sola Penna +10 more
doaj +1 more source
Atypical presentation of disseminated mycobacteriosis due to Mycobacterium avium in an aged cat
Australian Veterinary Journal, Volume 103, Issue 3, Page 121-126, March 2025.In cats, mycobacteriosis tends to present in a syndromic manner, with cases either being due to tuberculosis (TB) (in countries where TB is endemic), one of the “leprosy‐like” diseases affecting the skin and subcutis, panniculitis caused by infection of subcutaneous tissues generally with rapidly growing Mycobacteria spp.
A Teh +5 more
wiley +1 more source
Safety and Availability of Clofazimine in the Treatment of Multidrug and Extensively Drug-Resistant Tuberculosis: Analysis of Published Guidance and Meta-Analysis of Cohort Studies [PDF]
, 2013 Objectives: Given the spread of multidrug-resistant tuberculosis (MDR-TB), new therapies are urgently needed, including the repurposing of existing drugs. We aimed to assess key considerations for the clinical and programmatic use of clofazimine (Cfz), a
Dotsenko, Svetlana +9 more
core +1 more source
Bullous Type 2 Lepra Reaction: A Rare and Significant Case Report
Clinical Case Reports, Volume 13, Issue 1, January 2025.ABSTRACT Bullous type 2 lepra reactions are a rare initial presentation in leprosy that can complicate the disease with vesiculo‐bullous lesions. Early recognition and differentiation from other bullous disorders are critical for timely corticosteroid and multidrug therapy initiation to improve patient outcomes.
Hrithik Dakssesh Putta Nagarajan +6 more
wiley +1 more source
Combined therapy in leprosy : background and findings [PDF]
, 1978 This report is based on data obtained from 64 lepromatous cases. Despite many years of DDS monotherapy, the homogenates from biopsies of these patients revealed 104 or more bacteria.
Bonnici, Edgar +4 more
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Leprosy—Presenting as Rheumatoid Arthritis Misleading the Correct Diagnosis
Clinical Case Reports, Volume 13, Issue 1, January 2025.ABSTRACT Leprosy can present with symptoms resembling rheumatoid arthritis, leading to delays in diagnosis or inappropriate treatment, potentially progressing to lepromatous forms, neuropathy, and disability. Physicians must consider leprosy as a differential for rheumatoid arthritis, especially in endemic regions.
Dhakal Sagar +3 more
wiley +1 more source
A double-blind controlled clinical trial to assess the role of anti-histamines in the treatment of multi-bacillary leprosy [PDF]
, 1988 A double blind controlled clinical trial to assess the role of antihistamines as a supplement in the treatment of leprosy was conducted in multibacillary cases of leprosy.
Bhatia, V N +8 more
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Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection [PDF]
, 2008 Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which causes altered responsiveness to the bacterial pathogens.
Ivan Mikula Jr. +6 more
core +1 more source