Results 61 to 70 of about 6,867 (211)

Tumor necrosis factor promoter polymorphism and susceptibility to lepromatous leprosy.

, 1997
Genetically determined differences in immune responses to environmental agents may underlie susceptibility to many autoimmune and infectious diseases. Leprosy provides an example of a polarity in the type of immune response made to an infectious agent ...
Hazra, SK, Roy, S, Kwiatkowski, D, Saha, B, McGuire, W, Hill, Adrian, Mascie-Taylor, CG, Hill, AV   +7 more
core   +1 more source

Surface membrane changes in lepromatous macrophages affecting the adherence of Mycobacterium leprae [PDF]

, 1983
Macrophages from lepromatous leprosy patients showed poor adherence toMycobacterium leprae. The phagocytic activity of the macrophages was not correlated to the influence on the adherence ability.
Mahadevan, P. R., Lad, Shashikant J., Salgame, Padmini R.   +2 more
core   +1 more source

The Predictive Role of Biomarkers for Leprosy Prophylaxis in Contacts of Patients Who Are Indices of the Disease: A Systematic Review of the Literature

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Leprosy continues to be an important public health problem, particularly in endemic regions such as Brazil, India, and Indonesia. Household contacts of multibacillary (MB) patients represent a high‐risk group for subclinical infection due to prolonged exposure and high bacillary load.
Luiza Raquel Tapajós Figueira, Marcos Jessé Abrahão Silva, Lucas Vinicius Moraes da Silva, Rebecca Lobato Marinho, Keitty Anne Silva Neves, Thiago Augusto Ferreira dos Anjos, Lilian Cristina Santos Sinfronio da Silva, Daniele Melo Sardinha, Everaldina Cordeiro dos Santos, Luana Nepomuceno Gondim Costa Lima, Mirella Giovarelli   +10 more
wiley   +1 more source

Evidencing leprosy neuronal inflammation by 18-Fluoro-deoxy-glucose.

PLoS Neglected Tropical Diseases, 2023
BackgroundLeprosy is caused by multiple interactions between Mycobacterium leprae (M. leprae) and the host's peripheral nerve cells. M. leprae primarily invades Schwann cells, causing nerve damage and consequent development of disabilities.
Patricia Sola Penna, Sergio Augusto Lopes De Souza, Paulo Gustavo Limeira Nobre De Lacerda, Izabela Jardim Rodrigues Pitta, Clarissa Neves Spitz, Anna Maria Sales, Flavio Alves Lara, Ana Caroline Siquara De Souza, Euzenir Nunes Sarno, Roberta Olmo Pinheiro, Marcia Rodrigues Jardim   +10 more
doaj   +1 more source

Persistent Facial Nodules in an Elderly Patient

JEADV Clinical Practice, Volume 5, Issue 1, Page 319-322, March 2026.
Qian Ding, Qin‐Si Liu, Heng‐Guang Zhao   +2 more
wiley   +1 more source

Abundant Yet Aberrant T Helper Cell Responses to Candida albicans Underlie Mucosal Candidiasis in Humans and Mice

European Journal of Immunology, Volume 55, Issue 10, October 2025.
Th17 cells confer protection against Candida albicans infection. In patients with STAT1 gain‐of‐function (GOF) mutations and chronic mucocutaneous candidiasis (CMC), Candida‐specific Th cell responses are numerically preserved but skewed toward Th1 and Th2.
Camilla Basso, Corinne De Gregorio, Roberta Marzi, Florian Kirchner, Gabor Gyülveszi, Mélanie Migaud, Sinu Paul, Alessandro Sette, Antonio Lanzavecchia, Salomé LeibundGut‐Landmann, Jean‐Laurent Casanova, Anne Puel, Simone Becattini, Federica Sallusto   +13 more
wiley   +1 more source

LEPROMATOUS LEPROSY [PDF]

The Lancet, 1968
N B, Rabhan, D S, Waldorf
  +6 more sources

Widespread Skin Lesions in an Italian Man

JEADV Clinical Practice, Volume 5, Issue 1, Page 333-336, March 2026.
Rebecca Donadoni, Giulia Merlo, Gabriele Zanardi, Antonio Guadagno, Corrado Cabona, Stefania Artioli, Claudia Micalizzi, Emanuele Cozzani   +7 more
wiley   +1 more source

Serological Evidence of Soil‐Transmitted Helminth Infections as a Potential Risk for Severity in Leprosy Patients

Tropical Medicine &International Health, Volume 30, Issue 10, Page 1115-1123, October 2025.
ABSTRACT Leprosy presents a broad clinical spectrum influenced by the host's immune response, and co‐infections may further modulate disease progression. This study evaluated clinically diagnosed leprosy patients (n = 251) from Sergipe and Minas Gerais, Brazil, along with healthy controls (n = 43), soil‐transmitted helminths‐positive controls (n = 15),
Ana Laura Grossi de Oliveira, Augusto César Parreiras de Jesus, Ramayana Morais de Medeiros Brito, Jordânia Costa‐Pinto, Tatyane Martins Cirilo, José Bryan Rihs, Marcelo Eduardo Cardozo, Lilian Lacerda Bueno, Luisa Mourão Dias Magalhães, Ricardo Toshio Fujiwara   +9 more
wiley   +1 more source

Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) represents the most common form of leishmaniasis. It imposes a significant medical burden due to long‐lasting ulcers and disfiguring scars, underscoring the need for comprehensive CL control strategies, particularly in endemic regions.
Bahareh Abtahi‐Naeini, Seyed Naser Emadi, Zabihollah Shahmoradi, Mahsa Pourmahdi‐Boroujeni, Ali Saffaei, Fereshte Rastegarnasab   +5 more
wiley   +1 more source