Erythema Nodosum Leprosum in a Patient with Borderline Lepromatous Leprosy: A Case Report [PDF]
Background: Leprosy, caused by Mycobacterium leprae, presents on a spectrum ranging from tuberculoid to lepromatous disease. Borderline lepromatous leprosy represents an unstable immunological state that predisposes patients to immune-mediated reactions,
Guido Chiriboga +4 more
doaj +2 more sources
Lucio phenomenon: a case report on an overlooked reaction in lepromatous leprosy [PDF]
Our patient presented with a 5-year history of chronic, asymptomatic papulonodular lesions on the extremities. The lesions spread to the face and earlobes, with new ulcerative lesions on both legs for the past 8 months.
Natsuda Sajjachareonpong +5 more
doaj +2 more sources
Lucio Phenomenon and APLA in Hansen’s Disease: A Rare Phenomenon [PDF]
Lucio phenomenon (LP) is a rare reactional state seen in cases of diffuse lepromatous leprosy. Lucio leprosy is a pure, primitive, and diffuse form of lepromatous leprosy.
Jayanta Sharma +3 more
doaj +1 more source
T regulatory cells (TREG)(TCD4+CD25+FOXP3+) distribution in the different clinical forms of leprosy and reactional states [PDF]
BACKGROUND: Leprosy is characterized histologically by a spectrum of different granulomatous skin lesions, reflecting patients' immune responses to Mycobacterium leprae.
José Napoleão Tavares Parente +3 more
doaj +1 more source
Increase in TGF-β secreting CD4⁺CD25⁺ FOXP3⁺ T regulatory cells in anergic lepromatous leprosy patients. [PDF]
BACKGROUND: Lepromatous leprosy caused by Mycobacterium leprae is associated with antigen specific T cell unresponsiveness/anergy whose underlying mechanisms are not fully defined.
Chaman Saini +2 more
doaj +1 more source
Expression of NLRP3 inflammasome in leprosy indicates immune evasion of Mycobacterium leprae [PDF]
BACKGROUND Leprosy is an infectious-contagious disease caused by Mycobacterium leprae that remain endemic in 105 countries. This neglected disease has a wide range of clinical and histopathological manifestations that are related to the host ...
Ana Luisa Gomes Mendes +9 more
doaj +1 more source
Lucio Leprosy in Neglected Cases of Hansen’s Disease: A Series of Three Cases [PDF]
Lucio Leprosy is a rare form of Lepromatous leprosy, which normally occurs in chronic untreated patients of Hansen’s disease. Lucio phenomenon, was first reported from Mexico and henceforth commonly known as Mexican leprosy, but is now being ...
Rajkumar Kannan +3 more
doaj +1 more source
Leprosy in an Eight-Year-Old Child – An Exceptional Case with Unusual Oral Manifestation [PDF]
Leprosy is a contagious and granulomatous disease which is caused by Mycobacterium leprae. The incubation period for leprosy is five to seven years and it can take as long as about 30 years before signs and symptoms of leprosy develop in some patients ...
Mayuri Jain
doaj +1 more source
Role of S-100 Immunostaining in Demonstration of Nerve Changes and Quantification of Dendritic Cells in Leprosy [PDF]
Background: A definitive diagnosis of leprosy is based on a demonstration of either acid-fast bacilli or nerve elements within the granulomas. On routine hematoxylin and eosin stains, the nerve fibers are not easily identifiable. In this study, S-100
Anand Mohanraj, Sowmya Srinivasan
doaj +1 more source
Double trouble: a case of von Recklinghausen’s disease with coexistent lepromatous leprosy
Leprosy (or Hansen disease) is a tropical disease which affects the skin and nerves leading to deformities and disabilities. Von Recklinghausen's disease (neurofibromatosis 1) is a well-recognized genetic disorder with both cutaneous and systemic ...
Kaliaperumal Karthikeyan +2 more
doaj +1 more source

