Results 11 to 20 of about 402 (91)
AUTOINDUCTION PROPERTIES OF RIFAMPICIN ON JAVANESE TUBERCULOSIS WITH VARIANT TYPE CYP3A4*1G [PDF]
Rifampicin is one of the first-line anti-tuberculosis drugs. Rifampicin is metabolized by cytochrome P450 (CYP) 3A4. Polymorphisms of the CYP3A4gene will affect gene expression. This leads to impaired of formation of the enzyme.
Sutrisna, Em
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OBJETIVO: Analisar fatores associados à ocorrência de recidiva em hanseníase. MÉTODOS: Estudo retrospectivo caso-controle com 159 pacientes maiores de 15 anos diagnosticados com hanseníase em cinco municípios do estado de Mato Grosso, cujas unidades de ...
Silvana Margarida Benevides Ferreira +2 more
doaj
OBJETIVO: Estimar a frequência das deficiências físicas em pacientes tratados de hanseníase após alta medicamentosa e analisar sua distribuição espacial. MÉTODOS: Estudo descritivo transversal com 232 pessoas tratadas de hanseníase de 1998 a 2006.
Susilene Maria Tonelli Nardi +3 more
doaj
The Future of Teratology Research is In Vitro [PDF]
Birth defects induced by maternal exposure to exogenous agents during pregnancy are preventable, if the agents themselves can be identified and avoided.
Bailey, Jarrod +2 more
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Systems Toxicology: Mining chemical-toxicity signaling paths to enable network medicine [PDF]
Systems toxicology, a branch of toxicology that studies chemical effects on biological systems, presents exciting knowledge discovery challenges for the information researcher.
Desai, Kaushal D.
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Synthesis, Characterization and Biological activity of 1,3,4- Oxadiazole and 1,3,4- Thiadiazole Derivatives. [PDF]
Various substituted 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives have been synthesized by cyclising semicarbazone and thiosemicarbazone in presence of ferric chloride and citric acid to form 2-amino-5-substituted 1,3,4-oxadiazole and 1,3,4 ...
Smylin Ajitha Rani, S
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Multiple myeloma (MM) is a malignant neoplasm of bone marrow plasma B cells with high morbidity. Clofazimine (CLF) is an FDA-approved leprostatic, anti-tuberculosis, and anti-inflammatory drug that was previously shown to have growth suppression effects ...
Aliye Ezgi Gulec +6 more
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The Role of Macrophages in the Sequestration of Drug and Formation of Insoluble Drug Aggregates [PDF]
Drugs with poor aqueous solubility generally possess unfavorable pharmacokinetic properties. Upon oral administration, such drugs can form supersaturated solutions within the gastrointestinal tract, causing the formation of insoluble aggregates which may
Rzeczycki, Phillip
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Üre/tiyoüre grupları taşıyan sakarın ve isatin türevlerinin sentezi ve polifenol oksidaz enzim inhibisyonlarının incelenmesi [PDF]
06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması ...
Sönmez, Fatih
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Mitochondrial calcium uptake pathways as a potential therapeutic target [PDF]
It has been known since the 1960’s that mitochondria have a huge capacity to take up and accumulate calcium from the cytosol, regulating energy production, autophagy, and mitochondrial morphology.
Hill, JM
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