Results 11 to 20 of about 402 (91)

AUTOINDUCTION PROPERTIES OF RIFAMPICIN ON JAVANESE TUBERCULOSIS WITH VARIANT TYPE CYP3A4*1G [PDF]

open access: yes, 2015
Rifampicin is one of the first-line anti-tuberculosis drugs. Rifampicin is metabolized by cytochrome P450 (CYP) 3A4. Polymorphisms of the CYP3A4gene will affect gene expression. This leads to impaired of formation of the enzyme.
Sutrisna, Em
core   +2 more sources

Fatores associados à recidiva em hanseníase em Mato Grosso Factores asociados a recidiva en hanseníasis en Mato Grosso, Centro-oeste de Brasil Factors associated to relapse of leprosy in Mato Grosso, Central-Western Brazil

open access: yesRevista de Saúde Pública, 2011
OBJETIVO: Analisar fatores associados à ocorrência de recidiva em hanseníase. MÉTODOS: Estudo retrospectivo caso-controle com 159 pacientes maiores de 15 anos diagnosticados com hanseníase em cinco municípios do estado de Mato Grosso, cujas unidades de ...
Silvana Margarida Benevides Ferreira   +2 more
doaj  

Deficiências após a alta medicamentosa da hanseníase: prevalência e distribuição espacial Deficiencias posteriores a alta medicamentosa de hanseniasis: prevalencia y distribución espacial Leprosy-related disabilities after release from multidrug treatment: prevalence and spatial distribution

open access: yesRevista de Saúde Pública, 2012
OBJETIVO: Estimar a frequência das deficiências físicas em pacientes tratados de hanseníase após alta medicamentosa e analisar sua distribuição espacial. MÉTODOS: Estudo descritivo transversal com 232 pessoas tratadas de hanseníase de 1998 a 2006.
Susilene Maria Tonelli Nardi   +3 more
doaj  

The Future of Teratology Research is In Vitro [PDF]

open access: yes, 2005
Birth defects induced by maternal exposure to exogenous agents during pregnancy are preventable, if the agents themselves can be identified and avoided.
Bailey, Jarrod   +2 more
core   +1 more source

Systems Toxicology: Mining chemical-toxicity signaling paths to enable network medicine [PDF]

open access: yes, 2012
Systems toxicology, a branch of toxicology that studies chemical effects on biological systems, presents exciting knowledge discovery challenges for the information researcher.
Desai, Kaushal D.
core  

Synthesis, Characterization and Biological activity of 1,3,4- Oxadiazole and 1,3,4- Thiadiazole Derivatives. [PDF]

open access: yes, 2012
Various substituted 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives have been synthesized by cyclising semicarbazone and thiosemicarbazone in presence of ferric chloride and citric acid to form 2-amino-5-substituted 1,3,4-oxadiazole and 1,3,4 ...
Smylin Ajitha Rani, S
core  

Anti-Cancer Effects of Clofazimine As a Single Agent and in Combination with Cisplatin in Multiple Myeloma

open access: yes, 2016
Multiple myeloma (MM) is a malignant neoplasm of bone marrow plasma B cells with high morbidity. Clofazimine (CLF) is an FDA-approved leprostatic, anti-tuberculosis, and anti-inflammatory drug that was previously shown to have growth suppression effects ...
Aliye Ezgi Gulec   +6 more
core   +1 more source

The Role of Macrophages in the Sequestration of Drug and Formation of Insoluble Drug Aggregates [PDF]

open access: yes, 2018
Drugs with poor aqueous solubility generally possess unfavorable pharmacokinetic properties. Upon oral administration, such drugs can form supersaturated solutions within the gastrointestinal tract, causing the formation of insoluble aggregates which may
Rzeczycki, Phillip
core  

Üre/tiyoüre grupları taşıyan sakarın ve isatin türevlerinin sentezi ve polifenol oksidaz enzim inhibisyonlarının incelenmesi [PDF]

open access: yes, 2012
06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması ...
Sönmez, Fatih
core  

Mitochondrial calcium uptake pathways as a potential therapeutic target [PDF]

open access: yes, 2016
It has been known since the 1960’s that mitochondria have a huge capacity to take up and accumulate calcium from the cytosol, regulating energy production, autophagy, and mitochondrial morphology.
Hill, JM
core  

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