The Future of Teratology Research is In Vitro [PDF]
, 2005 Birth defects induced by maternal exposure to exogenous agents during pregnancy are preventable, if the agents themselves can be identified and avoided.
Bailey, Jarrod +2 more
core +1 more source
Pharmacokinetic Evaluation of the Penetration of Antituberculosis Agents in Rabbit Pulmonary Lesions
Antimicrobial Agents and Chemotherapy, 2011 Standard antituberculosis (anti-TB) therapy requires the use of multiple drugs for a minimum of 6 months, with variable outcomes that are influenced by a number of microbiological, pathological, and clinical factors.
M. Kjellsson +8 more
semanticscholar +1 more source
Systems Toxicology: Mining chemical-toxicity signaling paths to enable network medicine [PDF]
, 2012 Systems toxicology, a branch of toxicology that studies chemical effects on biological systems, presents exciting knowledge discovery challenges for the information researcher.
Desai, Kaushal D.
core
Synthesis, Characterization and Biological activity of 1,3,4- Oxadiazole and 1,3,4- Thiadiazole Derivatives. [PDF]
, 2012 Various substituted 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives have been synthesized by cyclising semicarbazone and thiosemicarbazone in presence of ferric chloride and citric acid to form 2-amino-5-substituted 1,3,4-oxadiazole and 1,3,4 ...
Smylin Ajitha Rani, S
core
, 2016 Multiple myeloma (MM) is a malignant neoplasm of bone marrow plasma B cells with high morbidity. Clofazimine (CLF) is an FDA-approved leprostatic, anti-tuberculosis, and anti-inflammatory drug that was previously shown to have growth suppression effects ...
Aliye Ezgi Gulec +6 more
core +1 more source
The Role of Macrophages in the Sequestration of Drug and Formation of Insoluble Drug Aggregates [PDF]
, 2018 Drugs with poor aqueous solubility generally possess unfavorable pharmacokinetic properties. Upon oral administration, such drugs can form supersaturated solutions within the gastrointestinal tract, causing the formation of insoluble aggregates which may
Rzeczycki, Phillip
core
Üre/tiyoüre grupları taşıyan sakarın ve isatin türevlerinin sentezi ve polifenol oksidaz enzim inhibisyonlarının incelenmesi [PDF]
, 2012 06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması ...
Sönmez, Fatih
core
Mitochondrial calcium uptake pathways as a potential therapeutic target [PDF]
, 2016 It has been known since the 1960’s that mitochondria have a huge capacity to take up and accumulate calcium from the cytosol, regulating energy production, autophagy, and mitochondrial morphology.
Hill, JM
core
Recurrent choriocarcinoma complicated with leprosy during chemotherapy: A case report and literature review. [PDF]
Medicine (Baltimore), 2023 Hu S, Lin X, Yin R, Wang W, Li Q.
europepmc +1 more source