Increase in TGF-β secreting CD4⁺CD25⁺ FOXP3⁺ T regulatory cells in anergic lepromatous leprosy patients. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND: Lepromatous leprosy caused by Mycobacterium leprae is associated with antigen specific T cell unresponsiveness/anergy whose underlying mechanisms are not fully defined.
Chaman Saini +2 more
doaj +1 more source
Expression of NLRP3 inflammasome in leprosy indicates immune evasion of Mycobacterium leprae [PDF]
Memorias do Instituto Oswaldo Cruz, 2020 BACKGROUND Leprosy is an infectious-contagious disease caused by Mycobacterium leprae that remain endemic in 105 countries. This neglected disease has a wide range of clinical and histopathological manifestations that are related to the host ...
Ana Luisa Gomes Mendes +9 more
doaj +1 more source
Lucio Leprosy in Neglected Cases of Hansen’s Disease: A Series of Three Cases [PDF]
Journal of Clinical and Diagnostic Research, 2023 Lucio Leprosy is a rare form of Lepromatous leprosy, which normally occurs in chronic untreated patients of Hansen’s disease. Lucio phenomenon, was first reported from Mexico and henceforth commonly known as Mexican leprosy, but is now being ...
Rajkumar Kannan +3 more
doaj +1 more source
Leprosy in an Eight-Year-Old Child – An Exceptional Case with Unusual Oral Manifestation [PDF]
Journal of Clinical and Diagnostic Research, 2017 Leprosy is a contagious and granulomatous disease which is caused by Mycobacterium leprae. The incubation period for leprosy is five to seven years and it can take as long as about 30 years before signs and symptoms of leprosy develop in some patients ...
Mayuri Jain
doaj +1 more source
Role of S-100 Immunostaining in Demonstration of Nerve Changes and Quantification of Dendritic Cells in Leprosy [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: A definitive diagnosis of leprosy is based on a demonstration of either acid-fast bacilli or nerve elements within the granulomas. On routine hematoxylin and eosin stains, the nerve fibers are not easily identifiable. In this study, S-100
Anand Mohanraj, Sowmya Srinivasan
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New Insight into the Pathogenesis of Erythema Nodosum Leprosum: The Role of Activated Memory T-Cells. [PDF]
, 2017 Memory T-cells, particularly, effector memory T cells are implicated in the pathogenesis of inflammatory diseases and may contribute to tissue injury and disease progression.
Abraham Aseffa +8 more
core +5 more sources
Double trouble: a case of von Recklinghausen’s disease with coexistent lepromatous leprosy
Journal of Infection in Developing Countries, 2011 Leprosy (or Hansen disease) is a tropical disease which affects the skin and nerves leading to deformities and disabilities. Von Recklinghausen's disease (neurofibromatosis 1) is a well-recognized genetic disorder with both cutaneous and systemic ...
Kaliaperumal Karthikeyan +2 more
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Dermatology Online Journal, 2008 Lepromatous leprosy is a form of chronic granulomatous disease that is caused by infection with Mycobacterium leprae. Early involvement is marked by widespread, ill-defined, erythematous papules and plaques. With early intervention, leprosy is a curable disease; however, if not recognized and treated promptly, permanent sequelae and disability result ...
Mahlberg, Matthew J, Levis, William R
openaire +4 more sources
Journal of Dermatology and Dermatologic Surgery, 2015 Lepromatous leprosy is usually generalized at diagnosis and may consist of erythematous macules, papules and nodules containing abundant Mycobacterium leprae and affecting wide spread areas of the skin.
Khalid M. Alwunais
doaj +1 more source
Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. [PDF]
, 2003 Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection.
Cogen, Anna L +4 more
core +1 more source