Coexistence of Scrofuloderma and Lepromatous Leprosy in Reaction: A Case Report. [PDF]
ABSTRACT Leprosy and tuberculosis (TB) are both chronic granulomatous infections caused by bacilli of the genus Mycobacterium. The simultaneous occurrence of cutaneous tuberculosis and leprosy is rare. We report a 56‐year‐old male presenting with painful erythematous nodules and plaques over the face and extremities for 1 week, along with asymptomatic ...
Khadka A +3 more
europepmc +2 more sources
A rare case of lepromatous leprosy in Germany. [PDF]
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 11, Page 1454-1456, November 2025.
Saternus R +8 more
europepmc +2 more sources
Uncommon Presentation of Lepromatous Leprosy in a Nonendemic Setting: A Case Report. [PDF]
Leprosy, caused by Mycobacterium leprae, remains a significant public health concern in certain endemic regions, but it is rarely encountered in nonendemic areas, posing diagnostic challenges. This case report discusses an unusual presentation of lepromatous leprosy in a patient residing in Saudi Arabia with no history of travel to endemic regions. The
Osman ME +6 more
europepmc +2 more sources
Revealing Erythema Nodosum Leprosum in a Leprosy Patient: A Case of Treatment Noncompliance. [PDF]
Lepra reactions (LR) are acute inflammatory conditions with immune mediators that are highly morbid. Patients with the lepromatous end of the leprosy spectrum (BL‐LL) are the only ones who develop Type‐2 LR. 90% of the time, it happens during or right after treatment, usually within 2 years.
Alhariri B +5 more
europepmc +2 more sources
Role of S-100 Immunostaining in Demonstration of Nerve Changes and Quantification of Dendritic Cells in Leprosy [PDF]
Background: A definitive diagnosis of leprosy is based on a demonstration of either acid-fast bacilli or nerve elements within the granulomas. On routine hematoxylin and eosin stains, the nerve fibers are not easily identifiable. In this study, S-100
Anand Mohanraj, Sowmya Srinivasan
doaj +1 more source
Unraveling Drug Resistance in <i>Mycobacterium leprae</i>: Exploring Genetic Mutations to Enhance Treatment Strategies for Human Leprosy-A Narrative Review. [PDF]
Leprosy, one of the oldest diseases, is caused by Mycobacterium leprae and Mycobacterium lepromatosis and continues to pose a significant global public health challenge despite decades of control efforts and the widespread use of multidrug therapy. Clinical manifestations range from tuberculoid to severe lepromatous forms, often accompanied by immune ...
Perera G +7 more
europepmc +2 more sources
New Insight into the Pathogenesis of Erythema Nodosum Leprosum: The Role of Activated Memory T-Cells. [PDF]
Memory T-cells, particularly, effector memory T cells are implicated in the pathogenesis of inflammatory diseases and may contribute to tissue injury and disease progression.
Abraham Aseffa +8 more
core +5 more sources
Double trouble: a case of von Recklinghausen’s disease with coexistent lepromatous leprosy
Leprosy (or Hansen disease) is a tropical disease which affects the skin and nerves leading to deformities and disabilities. Von Recklinghausen's disease (neurofibromatosis 1) is a well-recognized genetic disorder with both cutaneous and systemic ...
Kaliaperumal Karthikeyan +2 more
doaj +1 more source
Lepromatous leprosy is a form of chronic granulomatous disease that is caused by infection with Mycobacterium leprae. Early involvement is marked by widespread, ill-defined, erythematous papules and plaques. With early intervention, leprosy is a curable disease; however, if not recognized and treated promptly, permanent sequelae and disability result ...
Mahlberg, Matthew J, Levis, William R
openaire +4 more sources
Lepromatous leprosy is usually generalized at diagnosis and may consist of erythematous macules, papules and nodules containing abundant Mycobacterium leprae and affecting wide spread areas of the skin.
Khalid M. Alwunais
doaj +1 more source

