Results 61 to 70 of about 9,518 (197)

Lucio's phenomenon: exuberant case report and review of Brazilian cases [PDF]

Anais Brasileiros de Dermatologia, 2016
Lucio’s phenomenon is an uncommon reaction characterized by severe necrotizing cutaneous lesions that occurs in patients with Lucio’s leprosy and lepromatous leprosy. It is considered by some authors as a variant of type 2 or 3 reaction.
Rafael Henrique Rocha, Paulo Sergio Emerich, Lucia Martins Diniz, Marcela Bahia Barretto de Oliveira, Aline Neves Freitas Cabral, Ana Cristina Vervloet do Amaral   +5 more
doaj   +1 more source

Serological Evidence of Soil‐Transmitted Helminth Infections as a Potential Risk for Severity in Leprosy Patients

Tropical Medicine &International Health, Volume 30, Issue 10, Page 1115-1123, October 2025.
ABSTRACT Leprosy presents a broad clinical spectrum influenced by the host's immune response, and co‐infections may further modulate disease progression. This study evaluated clinically diagnosed leprosy patients (n = 251) from Sergipe and Minas Gerais, Brazil, along with healthy controls (n = 43), soil‐transmitted helminths‐positive controls (n = 15),
Ana Laura Grossi de Oliveira, Augusto César Parreiras de Jesus, Ramayana Morais de Medeiros Brito, Jordânia Costa‐Pinto, Tatyane Martins Cirilo, José Bryan Rihs, Marcelo Eduardo Cardozo, Lilian Lacerda Bueno, Luisa Mourão Dias Magalhães, Ricardo Toshio Fujiwara   +9 more
wiley   +1 more source

Quantitative lateral flow strip assays as user-friendly tools to detect biomarker profiles for leprosy [PDF]

, 2016
Leprosy is a debilitating, infectious disease caused by Mycobacterium leprae. Despite the availability of multidrug therapy, transmission is unremitting. Thus, early identification of M. leprae infection is essential to reduce transmission.
Alam, K. (Korshed), Corstjens, P.L.A.M. (Paul L. A. M.), De Dood, C.J. (Claudia J.), Eeden, S.J.F. (Susan) van den, Faber, R. (Roel), Geluk, A. (Annemieke), Richardus, J.H. (Jan Hendrik), Richardus, R. (Renate), Tjon Kon Fat, E.M. (Elisa M.), Van Hooij, A. (Anouk), Wilson, L. (Lindsay)   +10 more
core   +10 more sources

CD4+ Th17 cells discriminate clinical types and constitute a third subset of non Th1, Non Th2 T cells in human leprosy. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Patients with localized tuberculoid and generalized lepromatous leprosy show respectively Th1 and Th2 cytokine profile. Additionally, other patients in both types of leprosy also show a non discriminating Th0 cytokine profile with both ...
Chaman Saini, V Ramesh, Indira Nath
doaj   +1 more source

A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]

, 2017
Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James, Madigan, Cressida A, Ramakrishnan, Lalita   +2 more
core   +2 more sources

Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) represents the most common form of leishmaniasis. It imposes a significant medical burden due to long‐lasting ulcers and disfiguring scars, underscoring the need for comprehensive CL control strategies, particularly in endemic regions.
Bahareh Abtahi‐Naeini, Seyed Naser Emadi, Zabihollah Shahmoradi, Mahsa Pourmahdi‐Boroujeni, Ali Saffaei, Fereshte Rastegarnasab   +5 more
wiley   +1 more source

Leprosy in blood donors

Tropical Medicine &International Health, Volume 30, Issue 9, Page 1018-1022, September 2025.
Abstract Objectives We investigated the prevalence of anti‐phenolic glycolipid‐I (PGL‐I) IgM antibodies among temporarily unfit blood donors at the Pará State Blood Bank (HEMOPA), located in the Amazon region of northern Brazil. Using an arbitrary high cutoff for optical density (OD ≥0.750) in ELISA, a subset of donors was invited for clinical ...
Erika Vanessa Oliveira Jorge, Angélica Rita Gobbo, Izabelle Laissa Viana Costa, Raquel Carvalho Bouth, Sâmela Miranda da Silva, Ana Caroline Cunha Messias, Josafá Gonçalves Barreto, Patrícia Fagundes da Costa, Pablo Diego do Carmo Pinto, Moises Batista da Silva, John Stewart Spencer, Maurício Koury Palmeira, Claudio Guedes Salgado   +12 more
wiley   +1 more source

The role of the A C395 IFNGR1 mutation in determining susceptibility to intracellular infection in Malta [PDF]

, 2012
Background: The first human mycobacterial susceptibility gene was identified amongst four children on the island of Malta in 1995. All affected children were homozygous for a nonsense mutation at position 395 of the interferon gamma receptor 1 (IFNGR1 ...
Anderson, Suzanne T., Attard Montalto, Simon, Felice, Alex, Hibberd, Martin, Levin, Mike, Mangion, Mariella, Newport, Melanie J.   +6 more
core  

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, Volume 12, Issue 32, August 28, 2025.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Proceedings of a Joint Meeting held between The Norwegian Society of Infectious Diseases and the Royal Society of Tropical Medicine and Hygiene, Oslo, 20th June 2008 [PDF]

, 2009
The Royal Society of Tropical Medicine and Hygiene (RSTMH) has a tradition of holding joint meetings with fellow European Societies, providing opportunities to facilitate discussion, exchange information, foster mutual interests and develop collaboration
Myrvang, Bjorn, Newport, Melanie J.
core   +1 more source