Results 61 to 70 of about 9,180 (202)

The Predictive Role of Biomarkers for Leprosy Prophylaxis in Contacts of Patients Who Are Indices of the Disease: A Systematic Review of the Literature

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Leprosy continues to be an important public health problem, particularly in endemic regions such as Brazil, India, and Indonesia. Household contacts of multibacillary (MB) patients represent a high‐risk group for subclinical infection due to prolonged exposure and high bacillary load.
Luiza Raquel Tapajós Figueira, Marcos Jessé Abrahão Silva, Lucas Vinicius Moraes da Silva, Rebecca Lobato Marinho, Keitty Anne Silva Neves, Thiago Augusto Ferreira dos Anjos, Lilian Cristina Santos Sinfronio da Silva, Daniele Melo Sardinha, Everaldina Cordeiro dos Santos, Luana Nepomuceno Gondim Costa Lima, Mirella Giovarelli   +10 more
wiley   +1 more source

A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]

, 2017
Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James, Madigan, Cressida A, Ramakrishnan, Lalita   +2 more
core   +2 more sources

Abundant Yet Aberrant T Helper Cell Responses to Candida albicans Underlie Mucosal Candidiasis in Humans and Mice

European Journal of Immunology, Volume 55, Issue 10, October 2025.
Th17 cells confer protection against Candida albicans infection. In patients with STAT1 gain‐of‐function (GOF) mutations and chronic mucocutaneous candidiasis (CMC), Candida‐specific Th cell responses are numerically preserved but skewed toward Th1 and Th2.
Camilla Basso, Corinne De Gregorio, Roberta Marzi, Florian Kirchner, Gabor Gyülveszi, Mélanie Migaud, Sinu Paul, Alessandro Sette, Antonio Lanzavecchia, Salomé LeibundGut‐Landmann, Jean‐Laurent Casanova, Anne Puel, Simone Becattini, Federica Sallusto   +13 more
wiley   +1 more source

A double-blind controlled clinical trial to assess the role of anti-histamines in the treatment of multi-bacillary leprosy [PDF]

, 1988
A double blind controlled clinical trial to assess the role of antihistamines as a supplement in the treatment of leprosy was conducted in multibacillary cases of leprosy.
Bhatia, V N, Chandrasekaran, V, Hari, Lalitha, Kumar, Ashok, Nagarajan, M, Prabhakar, R, Roy, R G, Somasundaram, P R, Thomas, A   +8 more
core  

Persistent Facial Nodules in an Elderly Patient

JEADV Clinical Practice, Volume 5, Issue 1, Page 319-322, March 2026.
Qian Ding, Qin‐Si Liu, Heng‐Guang Zhao   +2 more
wiley   +1 more source

Serological Evidence of Soil‐Transmitted Helminth Infections as a Potential Risk for Severity in Leprosy Patients

Tropical Medicine &International Health, Volume 30, Issue 10, Page 1115-1123, October 2025.
ABSTRACT Leprosy presents a broad clinical spectrum influenced by the host's immune response, and co‐infections may further modulate disease progression. This study evaluated clinically diagnosed leprosy patients (n = 251) from Sergipe and Minas Gerais, Brazil, along with healthy controls (n = 43), soil‐transmitted helminths‐positive controls (n = 15),
Ana Laura Grossi de Oliveira, Augusto César Parreiras de Jesus, Ramayana Morais de Medeiros Brito, Jordânia Costa‐Pinto, Tatyane Martins Cirilo, José Bryan Rihs, Marcelo Eduardo Cardozo, Lilian Lacerda Bueno, Luisa Mourão Dias Magalhães, Ricardo Toshio Fujiwara   +9 more
wiley   +1 more source

Corneal Hypoaesthersia In Various Types Of Leprosy

Indian Journal of Dermatology, 1999
Four hundred leprosy patients comprising of 140 lepromatous leprosy, 72 borderline and 188 tuberculoid leprosy patients were examined for corneal hypoaesthesia.
Kumar Keshri Pradip, Pathak Ashok, Kar H. K, Sinha T. R. D   +3 more
doaj  

Polymorphisms in Toll-like receptor 4 ( TLR4 ) are associated with protection against leprosy [PDF]

, 2018
Accumulating evidence suggests that polymorphisms in Toll-like receptors (TLRs) influence the pathogenesis of mycobacterial infections, including leprosy, a disease whose manifestations depend on host immune responses.
Abraham, I., Aderem, A., Bochud, P.-Y, Britton, S., Hawn, T., Janer, M., Kaplan, G., Saunderson, P., Siddiqui, M., Sinsimer, D., Tadesse Argaw, A.   +10 more
core  

Widespread Skin Lesions in an Italian Man

JEADV Clinical Practice, Volume 5, Issue 1, Page 333-336, March 2026.
Rebecca Donadoni, Giulia Merlo, Gabriele Zanardi, Antonio Guadagno, Corrado Cabona, Stefania Artioli, Claudia Micalizzi, Emanuele Cozzani   +7 more
wiley   +1 more source

Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) represents the most common form of leishmaniasis. It imposes a significant medical burden due to long‐lasting ulcers and disfiguring scars, underscoring the need for comprehensive CL control strategies, particularly in endemic regions.
Bahareh Abtahi‐Naeini, Seyed Naser Emadi, Zabihollah Shahmoradi, Mahsa Pourmahdi‐Boroujeni, Ali Saffaei, Fereshte Rastegarnasab   +5 more
wiley   +1 more source