Results 61 to 70 of about 6,439 (198)

Analysis of clinical data and T helper 1/T helper 2 responses in patients with different clinical forms of leprosy

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Currently, there are no laboratory tests or sensitive and specific molecular markers for the early diagnosis of leprosy. The aim of this study was to analyze the clinical characteristics of patients with leprosy and investigate their ...
Ricardo Wilson de Pinho Rodrigues   +4 more
doaj   +1 more source

Tumor necrosis factor promoter polymorphism and susceptibility to lepromatous leprosy.

open access: yes, 1997
Genetically determined differences in immune responses to environmental agents may underlie susceptibility to many autoimmune and infectious diseases. Leprosy provides an example of a polarity in the type of immune response made to an infectious agent ...
Hazra, SK   +7 more
core   +1 more source

Lack of effects of the TNF-α and IL-10 gene polymorphisms in Mexican patients with lepromatous leprosy

open access: yes, 2012
Several human genetic variants have been associated with susceptibility or resistance to leprosy. The aim of this study was to assess whether gene polymorphisms of -308 G/A TNF-α and -819 T/C IL-10 are associated with lepromatous leprosy in Mexican ...
Murillo-Llanes, J.   +5 more
core  

T lymphocyte reactivity of leprosy patients and healthy contacts from a leprosy-endemic population to delipidified cell components of Mycobacterium leprae

open access: yes, 1994
In this study, we measured in vitro proliferative responses of peripheral blood mononuclear cells from both leprosy patients across the clinical spectrum and also healthy contacts from a leprosy-endemic population to delipidified cell components of ...
Ramu, G.   +5 more
core   +1 more source

Lucio phenomenon: a case report on an overlooked reaction in lepromatous leprosy

open access: yesDermatology Reports
Our patient presented with a 5-year history of chronic, asymptomatic papulonodular lesions on the extremities. The lesions spread to the face and earlobes, with new ulcerative lesions on both legs for the past 8 months.
Natsuda Sajjachareonpong   +5 more
doaj   +1 more source

Clinical variables associated with disability in leprosy cases in northeast Brazil

open access: yesJournal of Infection in Developing Countries, 2015
Introduction: The clinical outcomes of leprosy include complications such as physical disabilities and deformities that vary according to the degree of impairment of nerve trunks.
Victor Santana Santos   +7 more
doaj   +1 more source

Vasculitic neuropathy in a patient with inactive treated lepromatous leprosy

open access: yes, 2000
A 46 year old Asian male with previously treated lepromatous leprosy developed a stepwise multifocal sensory disturbance 25 years later. Neurophysiology demonstrated marked deterioration from previous studies.
Bowen, J R C   +4 more
core   +1 more source

Lepromatous Leprosy [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1973
Sheila M Johnston   +2 more
openaire   +3 more sources

Renal involvement in leprosy: retrospective analysis of 461 cases in Brazil

open access: yesBrazilian Journal of Infectious Diseases
BACKGROUND: Renal lesions in leprosy have been extensively described, including amyloidosis, glomerulonephritis, nephrosclerosis, tubulointerstitial nephritis and granulomas.
Geraldo Bezerra da Silva Júnior   +1 more
doaj   +1 more source

Leprosy Specific Orofacial Aspects

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2011
Leprosy is a chronic infection caused by Mycobactenum leprae, GHA- Hansen first identified the organism in 1873, so called Hansen disease. Mycobacterium leprae is a bacillus that presents a peculiar tropism for the skin and peripheral nerves.
Vathsala Naik   +3 more
doaj   +1 more source

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