Results 141 to 150 of about 40,192 (253)

Antiglioma effects of cytarabine on leptomeningeal metastasis of high-grade glioma by targeting the PI3K/Akt/mTOR pathway

, 2017
Kai-Hong Zhao,1 Can Zhang,2 Yue Bai,1 Yan Li,1 Xun Kang,1 Jian-Xin Chen,1 Kun Yao,3 Tao Jiang,4 Xiao-Song Zhong,2 Wen-Bin Li1 1Department of Glioma, 2Clinical Center of Gene And Cell Engineering, Beijing Shijitan Hospital, 3Department of Neurosurgery ...
Yao K, Li WB, Li Y, Kang X, Zhao KH, Zhong XS, Chen JX, Jiang T, Zhang C, Bai Y   +9 more
core  

Pitfalls in diagnosing and long‐term management of ceroid lipofuscinosis NCL4A in a mixed‐breed dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract An 8‐year‐old, spayed, female, mixed‐breed dog was presented with a 9‐month history of occasionally stumbling on walks, having difficulty navigating stairs and jumping into the car. A prior computed tomography scan of the head revealed mild leptomeningeal enhancement and suggested meningoencephalitis.
Ingeborg Hein, Ines Heinreich, Florian Willmitzer, Marion Mucha   +3 more
wiley   +1 more source

Clinical and radiological stabilization following vutrisiran treatment in transthyretin leptomeningeal amyloidosis: a case report

Clinical and radiological stabilization following vutrisiran treatment in transthyretin leptomeningeal amyloidosis: a case ...
Longhi, Simone, Rinaldi, Rita, Riefolo, Mattia, Palombo, Flavia, Conti, Alfredo, Vaisfeld, Alessandro, Foschini, Maria Pia, Spinardi, Luca, Guaraldi, Pietro, Guarino, Maria, Rossi, Simone, Mastrangelo, Andrea   +11 more
core   +1 more source

Clinical and MRI findings of suspected cerebrospinal nematodiasis in an alpaca

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 5‐year‐old alpaca was presented with a 2‐week history of progressive pelvic limb ataxia and paresis. Neurological examination localised the lesion to the thoracolumbar spinal cord. Magnetic resonance imaging (MRI) of the cervical and thoracolumbar spine revealed no abnormalities; however, contrast‐enhanced sequences were not performed due to
Aurelia Gasser, Mireille Meylan, Alexane Durand, Veronika Stein, Arianna Maiolini   +4 more
wiley   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for ependymomas

Brain Pathology, Volume 36, Issue 6, November 2026.
Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (ADAPTR) recommendations for ependymomas in resource‐restrained settings (RL = resource level; created in BioRender). Abstract Ependymomas are uncommon primary tumors of the central nervous system (CNS) that affect both children and adults.
Laveniya Satgunaseelan, Michael E. Buckland, Geeta Chacko, Kenta Masui, Junji Shibahara, Vani Santosh, Maysa Al‐Hussaini, Sung‐Hye Park, Tarik Tihan, Ho‐Keung Ng, Pieter Wesseling, David N. Louis, Chitra Sarkar, Takashi Komori   +13 more
wiley   +1 more source

Convergence of Cerebrospinal Fluid Neuronal Biomarker Burden and MRI Lesion Pattern and Its Association With Short‐Term Outcome in Neuroinfectious Diseases

European Journal of Neurology, Volume 33, Issue 11, November 2026.
In 123 patients with neuroinfectious diseases, temporal lobe involvement on MRI was associated with higher CSF neuronal biomarkers. Both temporal lobe involvement and global CSF neuronal biomarker burden were independently associated with outcome at discharge. MRI and CSF biomarkers thus provide complementary aspects of disease severity.
Lucio D'Anna, Deborah K. Erhart, Franz Felix Konen, Christopher M. Weise, Makbule Senel, Caroline Stapf, Dominica Hudasch, Petra Steinacker, Lorenzo Barba, Patrick Oeckl, Jonas Ranke, Nicola Ticozzi, Federico Verde, Steffen Halbgebauer, Thomas Skripuletz, Kurt‐Wolfram Sühs, Hayrettin Tumani, Markus Otto, Samir Abu‐Rumeileh   +18 more
wiley   +1 more source

Early Hints of Metagenome Next‐Generation Sequencing and Copy Number Variations Analysis: An Occult Case of Leptomeningeal Metastasis With Rapid Cognitive Decline

Clinical Case Reports
Early detection and treatment are critical for improving the prognosis of patients with leptomeningeal metastasis. However, heterogeneous clinical manifestations, non‐specific imaging, and limited sensitivity of cerebrospinal fluid cytology posed ...
Xueqin Chen, Haotao Zheng, Taoli Wang, Ziyang Feng, Jia Wang, Yangsicheng Liu, Wenxin Qin, Fanxin Kong, Xiude Qin   +8 more
doaj   +1 more source

Evolving role of proton therapy in contemporary oncology

Cancer, Volume 132, Issue 20, 15 October 2026.
Abstract Proton therapy offers a distinct physical advantage over photon radiotherapy through the Bragg peak dose concentration in target with both lower integral dose and finite path length, and sharper penumbra as compared to photons, collectively reducing radiation exposure to surrounding normal tissues and potentially improving the therapeutic ...
Emily S. Lebow, Helen A. Shih
wiley   +1 more source

Leptomeningeal carcinomatosis arising from esophageal cancer: a systematic review of the literature. [PDF]

Dis Esophagus
Mylonakis A, Stylios D, Tsilimigras D, Charalampopoulos G, Kotsantis I, Liontos M, Georgakopoulos I, Schizas D.   +7 more
europepmc   +1 more source

Case Report: Isolated leptomeningeal relapse after systemic control in PALB2-altered pancreatic cancer. [PDF]

Front Med (Lausanne)
Yuan J, Xu Y, Zhou Q, Yuan G, Ye M.
europepmc   +1 more source