Results 161 to 170 of about 112,162 (295)

FSP1 as the convergent hub of autophagy and ubiquitination governing ferroptosis in monocrotaline‐induced pulmonary arterial hypertension

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Background: The crosstalk between autophagy and ferroptosis in pulmonary arterial hypertension (PAH) remains unclear. We investigated the role of FSP1 as a critical link between these processes. Methods and Findings: Mechanistically, we identified that FSP1 degradation is dually regulated by NBR1‐mediated autophagic flux and RNFT1‐dependent K63‐linked ...
Dandan Chen, Qi Jin, Lei Zhang, Wenzhi Pan, Daxin Zhou, Junbo Ge, Lihua Guan   +6 more
wiley   +1 more source

Falar, ler e escrever no Jardim de Infância : como a investigação suporta a ação

, 2019
O programa Falar, ler e escrever no jardim de infância – FLE-JI resultou da integração e reflexão de dois projetos de intervenção no âmbito da literacia emergente – Melhor falar para melhor ler (Viana, 2001) e uma linha de ação do projeto Litteratus ...
Costa, Lurdes, Ribeiro, Iolanda, Brandão, Sara, Baptista, Adriana, Viana, Fernanda Leopoldina, Santos, Sandra   +5 more
core   +1 more source

«@Ler e a Ler» leituras para todos os gostos…

, 2010
Como se faz um leitor? Ou melhor como se recupera um leitor e optimiza os que já sentem o apelo pela leitura? Estas questões são cruciais para qualquer professor ou para qualquer professor que desempenhe a função de Coordenador de uma Biblioteca Escolar.
openaire   +2 more sources

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source

No effect of short‐term exposure to ocean acidification on individual‐level variation in behaviour and susceptibility to predation in a Great Barrier Reef damselfish

Journal of Animal Ecology, Volume 95, Issue 11, Page 2263-2276, November 2026.
This study shows that projected ocean acidification does not alter behaviour or predation risk in coral reef fish, challenging earlier assumptions. By quantifying consistent individual‐level behavioural differences and relating individual traits to survival during a live‐predation trial, it also provides evidence for a boldness–predation trade‐off in a
Dominique G. Roche, Josefin Sundin, Ben Speers‐Roesch, Shinichi Nakagawa, Timothy D. Clark, Sandra A. Binning   +5 more
wiley   +1 more source

Scaling/LER study of Si GAA nanowire FET using 3D Finite Element Monte Carlo simulations

Joint International EUROSOI Workshop and International Conference on Ultimate Integration on Silicon, 2016
M. Elmessary, D. Nagy, M. Aldegunde, N. Seoane, G. Indalecio, Jari Lindberg, W. Dettmer, D. Perić, A. García-Loureiro, K. Kalna   +9 more
semanticscholar   +1 more source

Differential Varietal Responses in Faba Bean Concerning Pea Aphid and Pea Necrotic Yellow Dwarf Virus (PNYDV) When Intercropped With Oat

Journal of Applied Entomology, Volume 150, Issue 9, Page 1253-1267, November 2026.
ABSTRACT The pest status of pea aphid (Acyrthosiphum pisum H.) in faba bean (Vicia faba L.) cultivation has gained importance because it transmits Pea necrotic yellow dwarf virus (PNYDV), a novel nanovirus in Europe. This study evaluated two faba bean varieties, ‘Fuego’ and ‘GL Sunrise’, grown under sole crop (SC) and intercrop (IC) conditions with oat
Ahmed Berawe, Heiko Ziebell, Judith Nora Seeger, Helmut Saucke   +3 more
wiley   +1 more source

Tipos de leitor e modos de ler no século XXI [PDF]

, 2000
Este artigo tem por objetivo caracterizar algumas das maneiras de ler na sociedade, o que implica procurar entender como se dá o encontro entre o leitor e o texto. Ler não é só a compreensão do objeto lido. Ler é
Parahyba, Martha Ribeiro
core  

Isozyme‐Specific Inhibition of GSK‐3 Reveals Distinct Cellular Responses in Huntington's Disease Fibroblasts

Journal of Neurochemistry, Volume 170, Issue 11, November 2026.
Using skin fibroblasts from people with Huntington's disease, we compared selective inhibition of the two forms of the protein kinase GSK‐3. Inhibiting either GSK‐3α or GSK‐3β reduced a signaling pathway involved in cell growth and metabolism.
Yarine Lugassy, Eva Berent, Sandra Jeries, Tamar Ziv, Hagit Eldar‐Finkelman   +4 more
wiley   +1 more source

Ler um sintoma

, 2011
Afreudite : Revista Lusófona de Psicanálise Pura e AplicadaEste texto chama a atenção para o facto da psicanálise não ser só uma questão de saber escutar, mas também de saber ler, em particular de ler o real dos restos sintomáticos para além do sentido ...
Miller, Jacques-Alain
core