Results 81 to 90 of about 2,111,371 (205)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Análisis del perfil de flexibilidad en jóvenes taekwondistas

open access: yesRevista de Artes Marciales Asiáticas, 2018
El objetivo principal del presente estudio fue determinar el perfil de flexibilidad de la extremidad inferior en atletas jóvenes de taewwondo, así como identificar los deportistas con cortedad muscular.
Antonio Cejudo Palomo   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Lesion Bypass and the Reactivation of Stalled Replication Forks

open access: yesAnnual Review of Biochemistry, 2018
Accurate transmission of the genetic information requires complete duplication of the chromosomal DNA each cell division cycle. However, the idea that replication forks would form at origins of DNA replication and proceed without impairment to copy the ...
K. Marians
semanticscholar   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Reparación anatómica del bíceps distal por un abordaje anterior sin el uso de implantes: resultados clínicos y funcionales

open access: yesRevista de la Asociación Argentina de Ortopedia y Traumatología
Introducción: Existen múltiples enfoques quirúrgicos para abordar las lesiones del bíceps distal, con diferentes tasas de éxito y complicaciones asociadas.
Ignacio Seré   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

La importancia del tratamiento inicial adecuado en una quemadura subdérmica en miembro inferior. Caso clínico

open access: yesGerokomos, 2018
RESUMEN La quemadura es una lesión térmica multicausal que afecta a diferentes tejidos corporales. En miembro inferior se complican con síndrome posflebítico, cicatrices retráctiles y disfunciones motoras, por lo que el diagnóstico precoz y el ...
Jordi Guinot-Bachero   +4 more
doaj  

Validez de constructo y utilidad clínica del Trunk control test versión argentina en sujetos con secuela de lesión medular espinaln secuela de lesión medular espinal

open access: yesRevista del Hospital Italiano de Buenos Aires
Introducción: aquellas personas con buen control de tronco poseen una mayor probabilidad de realizar por sí mismas  actividades de la vida diaria independientemente del nivel de lesión y del grado de lesión; pero hasta el momento no contamos en la ...
Gerardo Candoni   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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