Results 101 to 110 of about 1,207,332 (240)

Disfunción renal secundaria a lesión medular aguda

open access: yes, 2017
La lesión medular es el daño a cualquier parte de la médula espinal que resulta en cambios permanentes o temporales de las funciones motoras, sensitivas o autonómicas por debajo de la lesión.
Lazcano Romano, Itzel   +2 more
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Conferencia ‘Identificación del riesgo de lesión en jóvenes deportistas. ¿Es posible prevenir la lesión deportiva?’

open access: yes, 2018
Descripción: El lunes 18 de diciembre, a las 19:30 h, Pilar Sainz de Baranda, profesora de la Facultad de Ciencias del Deporte de la Universidad de Murcia, impartirá la conferencia ‘Identificación del riesgo de lesión en jóvenes deportistas. ¿Es posible
OMEGA, FOTOS
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Traumatismo cerrado con lesión vertebro-medular

open access: yes
100 CASOS EN EL PACIENTE POLITRAUMATIZADO F. Turégano Fuentes, P. Ottolino Lavarte, M.D. Pérez Díaz, S. Navarro Soto and J. Aranda Narváez. Editorial PANAMERICANA. 382 páginas.
Martín García, Sergio   +2 more
core  

Cambios en la vida sexual de la persona con lesión medular [PDF]

open access: yes, 2012
La sexualidad es parte integral del ser humano y forma parte de sus varias actividades de vida. Debido a la limitación consecuente de la lesión, el portador de lesión medular enfrenta cambios significativos en su vida sexual.
Holanda Cavalcante, Karenine María   +3 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

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