Results 21 to 30 of about 515 (108)

Studying When to Add Biological Therapy to Cytotoxic Therapy in Advanced Cancer Care Using Real World Data: How to Avoid Design Choices That Generate Immortal Time

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Since real‐world data lack information on treatment assignment (usually the only information available is treatment prescription/administration) and early outcomes can happen in advanced cancer, some design choices may introduce immortal time due to selection or due to treatment strategy misclassification.
Xabier Garcia‐Albeniz, Julia Vila‐Guilera, Manuel Zamparini, Helena Oliveres, Vicente Alonso‐Orduna, Jaime Feliu, Ana Fernández‐Montes, Marta Martín‐Richard, Elisa Gálvez‐Munoz, Ana Ruiz‐Casado, Alfonso Yubero‐Esteban, Jorge Aparicio, Julia Alcaide‐Garcia, Javier Gallego Plazas, Carlos Fernandez‐Martos, Rosa Gallego‐Sanchez, Mónica Guillot Morales, Rubén Leno, Francis Esposito, Sandra Lopez‐Prades, Míriam Cuatrecasas, Barbra A. Dickerman, Joan Maurel   +22 more
wiley   +1 more source

Diagnosis and treatment of endoparasites in pet rabbits

In Practice, Volume 48, Issue 5, Page 258-265, June 2026.
Background: Rabbits are popular pets and members of the veterinary team play a critical role both as providers of species‐specific medical care and a source of informed advice regarding husbandry and preventive medicine. Rabbits can potentially be infected with a somewhat bewildering array of endoparasites, but pathogenicity and significance of ...
Kate Hughes, Richard Saunders
wiley   +1 more source

Collagen and microvascular alterations contribute to neuromuscular degeneration and disease progression in chronic intestinal pseudo‐obstruction

Journal of Internal Medicine, Volume 299, Issue 5, Page 587-603, May 2026.
Abstract Background Chronic intestinal pseudo‐obstruction (CIPO) is a severe gastrointestinal motility disorder that may be idiopathic or associated with systemic disease. In idiopathic cases, the pathophysiological mechanisms remain poorly defined. Although mutations in angiogenic factors have been reported in mitochondrial forms of CIPO, their role ...
Elisa Boschetti, Irene Neri, Leonardo Caporali, Elena Bonora, Carolina Malagelada, Claudio Fiorini, Danara Ormanbekova, Alessandro Berghella, Roberto D'Angelo, Rita Rinaldi, Cristiana Caliceti, Anna Costanzini, Mirella Falconi, Vincenzo Stanghellini, Stefano Ratti, Lucia Manzoli, Valerio Carelli, Roberto De Giorgio   +17 more
wiley   +1 more source

Actitud a seguir ante la detección de una lesión focal inferior o igual a 2 cm de tamaño en un paciente con cirrosis hepática [PDF]

, 2010
[spa] ANTECEDENTES: El diagnóstico precoz del carcinoma hepatocelular es la única opción para poder aplicar tratamientos radicales potencialmente curativos. Por este motivo es necesario desarrollar diferentes técnicas que permitan realizar el diagnóstico
Forner González, Alejandro
core  

NR3C1, LAX1, and RCAN3 as Circulating Epigenetic Biomarkers for Prognosis and Chemotherapy Response Prediction in Metastatic Pancreatic Cancer

MedComm, Volume 7, Issue 4, April 2026.
Clinical utility of liquid biopsy‐based epigenetic profiling in PDAC management. Aberrant methylation of LAX1, RCAN3, and NR3C1 was identified in cfDNA from mPDAC patients, highlighting their potential as non‐invasive epigenetic biomarkers. Methylation levels of these genes showed prognostic value, supporting their relevance for patient stratification ...
Pablo Cano‐Ramírez, Marta Toledano‐Fonseca, María Teresa Cano‐Osuna, Nerea Herrera‐Casanova, Emilio Carrillo‐Pecero, Antonio Rodríguez‐Ariza, Enrique Aranda, María Victoria García‐Ortiz   +7 more
wiley   +1 more source

Conducta a seguir ante una lesión hepática focal reportada por imagenología. Parte II. [PDF]

, 2006
En el presente artículo se reportan las posibilidades diagnósticas más frecuentes, así como la estrategia recomendada para esclarecer el origen ante la sospecha de lesiones hepáticas focales primarias o secundarias de origen ...
Soler Porro, Luís Laureano, Martínez Sarmiento, Alberto, Camacho Assef, José Antonio   +2 more
core   +1 more source

Prevalencia de lesiones focales hepáticas diagnosticadas por tomografía, en pacientes del departamento de imagenología, Hospital José Carrasco Arteaga, Cuenca. Enero-Diciembre 2013 [PDF]

, 2015
Objetivo. Determinar la Prevalencia de Lesiones Focales Hepáticas diagnosticadas mediante Tomografía en pacientes del Hospital José Carrasco Arteaga; durante el periodo Enero-Diciembre 2013. Metodología.
Sarmiento Segovia, Jessica Maribel, Fajardo Loja, Mónica Fernanda, Gavilanez Guerrero, Ricardo Daniel   +2 more
core  

Clinical Trial: Early Nivolumab Addition to Regorafenib in Patients With Hepatocellular Carcinoma in Second‐Line (The GOING Trial)

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 7, Page 955-966, April 2026.
In the phase I/IIa GOING trial, an add‐on strategy with regorafenib followed by nivolumab showed a manageable safety profile and meaningful clinical activity in second‐line hepatocellular carcinoma, with a median overall survival of 25 months and 45% three‐year survival in sorafenib‐experienced patients.
Marco Sanduzzi‐Zamparelli, Ana Matilla, José Luis Lledo, Sergio Muñoz‐Martínez, María Varela, Mercedes Iñarrairaegui, Christie Perelló, Beatriz Mínguez, Neus Llarch, Laura Márquez, Antonio Guerrero, Gemma Iserte, Andrés Castaño‐García, Laura Carrión, Marta Fortuny, Jordi Rimola, Ángeles García‐Criado, Gema Domenech, Ferran Torres, José Rios‐Guillermo, Loreto Boix, Esther Samper, Àngels Kateb, Jordi Bruix, Maria Reig   +24 more
wiley   +1 more source

Identificación de lesiones focales hepáticas mediante tomografía multicorte en el Hospital Nacional “Daniel Alcides Carrión”- Callao 2017 [PDF]

, 2019
Objetivo: Identificar las lesiones focales hepáticas mediante tomografía multicorte en el Hospital Nacional “Daniel Alcides Carrión”- Callao 2017. Metodología: estudio de tipo observacional, de diseño descriptivo, retrospectivo y de corte transversal. Se
Córdova López de Tequén, Martha Aurora
core  

Pathological and Epidemiological Assessment of Trematode Burden in Ruminants From Central Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
• Trematode infections were highly prevalent (49.22%) among ruminants in central Ethiopia, with fasciolosis (32.42%) and paramphistomosis (16.80%) strongly associated with poor body condition and specific geographic origins. • Histopathological and haematological analyses revealed severe liver and intestinal damage, anaemia, and elevated liver enzymes,
Adisu Wakuma Boke, Yacob Hailu Tolosa, Abdi Feyisa Fufa, Jirata Shiferaw Abosse   +3 more
wiley   +1 more source