Results 1 to 10 of about 21,570 (177)

Subacute edema progression after acute ischemic stroke: impact of intravenous alteplase administration and reperfusion degree [PDF]

Frontiers in Neurology
IntroductionAlteplase is known to increase the risk of blood-brain barrier integrity disruption, potentiating hemorrhage and edema. Evolving edema reduces chances of good functional outcomes.
Wiktor Olszewski, Wiktor Olszewski, Fabiano Cavalcante, Laura van Poppel, Laura van Poppel, Ludo Beenen, Bart J. Emmer, Ido van den Wijngaard, Ido van den Wijngaard, Robin Lemmens, Robin Lemmens, Yvo Roos, Henk Marquering, Henk Marquering, Praneeta Konduri, Praneeta Konduri, Praneeta Konduri, Charles Majoie   +17 more
doaj   +2 more sources

A Comparative Study of Variables Influencing Ischemic Injury in the Longa and Koizumi Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in Mice. [PDF]

PLoS ONE, 2016
The intraluminal filament model of middle cerebral artery occlusion (MCAO) in mice and rats has been plagued by inconsistency, owing in part to the multitude of variables requiring control.
Gary P Morris, Amanda L Wright, Richard P Tan, Amadeus Gladbach, Lars M Ittner, Bryce Vissel   +5 more
doaj   +1 more source

EARLY AND REMOTE RESPONSE OF HIF-1Α PROTEIN IN THE HIPPOCAMPUS FIELDS TO ISCHEMIA-REPERFUSION IN RATS WITH DIABETES MELLITUS

Східноукраїнський медичний журнал, 2021
Introduction. The role of the transcription factor Hif-1α in pathogenesis of hypoxic lesions and diabetes mellitus (DM) has been confirmed, though molecular mechanisms underlying dysfunctions of the factor in the association of DM with ischemic ...
O. M. Nika, O. V. Zaliavska, O. V. Kaushanska   +2 more
doaj   +1 more source

Reduced Post-ischemic Brain Injury in Transient Receptor Potential Vanilloid 4 Knockout Mice

Frontiers in Neuroscience, 2020
Background and PurposeIn the acute phase of ischemia-reperfusion, hypoperfusion associated with ischemia and reperfusion in microvascular regions and disruption of the blood–brain barrier (BBB) contribute to post-ischemic brain injury.
Koji Tanaka, Shoji Matsumoto, Takeshi Yamada, Ryo Yamasaki, Makoto Suzuki, Mizuho A. Kido, Jun-Ichi Kira   +6 more
doaj   +1 more source

Ischemic post-conditioning in acute ischemic stroke thrombectomy: A phase-I duration escalation study

Frontiers in Neuroscience, 2022
BackgroundPrevious experimental studies have found that ischemic post-conditioning exhibits neuroprotective effects by alleviating ischemia-reperfusion injury in an acute ischemic stroke model, and its efficacy is thought to be related to the duration of
Longfei Wu, Bohao Zhang, Wenbo Zhao, Xunming Ji, Xunming Ji, Ming Wei, Ming Wei, Ming Wei   +7 more
doaj   +1 more source

Role of Left Ventricular Twist and Torsion in Assessment of Reperfusion in Acute ST-Elevation Myocardial Infarction Patients [PDF]

International Journal of Medical Arts, 2020
Background: Myocardial infarction is an acute emergency which needs rapid assessment, especially for myocardial reperfusion. Aim of the work: To evaluate left ventricle [LV] twist/torsion for assessment of myocardial reperfusion after acute ST-elevation
Ayman Gad, Mohamed Bashandy, Abd Elrahman Sharaf   +2 more
doaj   +1 more source

Preconditioning with L-alanyl-glutamine upon cerebral edema and hypocampus red neurons counting in rats subjected to brain ischemia /reperfusion injury [PDF]

Acta Cirúrgica Brasileira, 2015
PURPOSE:To evaluate the effects of the dipeptide L-alanyl-glutamine (L-Ala-Gln) as a preconditioning agent to potentially promote reduction in the intensity of lesion or induction of resilience in rats subjected to global cerebral ischemia/reperfusion (I/
Paulo Roberto Cavalcante de Vasconcelos, André Brito Bastos Guimarães, Marcio Wilker Soares Campelo, Paulo Roberto Leitão de Vasconcelos, Sergio Botelho Guimaraes   +4 more
doaj   +1 more source

Sonothrombolysis Augments Reperfusion in ST-Elevation Myocardial Infarction With Primary Percutaneous Coronary Intervention: Insights From the SONOSTEMI Study

CJC Open, 2022
Reperfusion injury is common following primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction. In a prospective Canadian single-arm study of 15patients, the use of myocardial contrast echocardiography with high mechanical ...
Kevin R. Bainey, MD, MSc, Ahmed Abulhamayel, MD, Amir Aziz, MRCP, PhD, Harald Becher, MD, PhD   +3 more
doaj   +1 more source

Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model

iScience, 2022
Summary: Extracellular ATP released to the ischemic brain parenchyma is quickly metabolized by ectonucleotidases. Among them, the ecto-5′-nucleotidase CD73 encoded by Nt5e generates immunosuppressive adenosine.
Ines Sophie Schädlich, Oliver Schnapauff, Lennart Pöls, Jürgen Schrader, Eva Tolosa, Björn Rissiek, Tim Magnus   +6 more
doaj   +1 more source

Dynamics of cerebral lipid peroxidation processes and antioxidant defence in rats with streptozotocin-induced diabetes complicated by ischemic-reperfusion lesion of the brain

Journal of Education, Health and Sport, 2017
Introduction. The role of oxidative stress in the pathogenesis of ischemic-reperfusion lesions and diabetes mellitus (DM) has been evidenced, although the dynamics of its parameters in case of DM complicated by ischemic-reperfusion lesion of the brain ...
O. V. Тkachuk, M. A. Povar
doaj   +3 more sources