Results 141 to 150 of about 21,570 (177)

Engineering a Tumor‐Targeted MgH2@Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation

open access: yesRare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu   +5 more
wiley   +1 more source

Advances in Engineered Extracellular Vesicles for the Treatment of Atherosclerosis and Atherothrombosis – Next‐Generation Cardiovascular Nanomedicine

open access: yesSmall Structures, Volume 7, Issue 3, March 2026.
Exosomes (small extracellular vesicles) are nanosized vesicles produced naturally by living cells. They can be engineered by various techniques to deliver biologically active molecules to injury sites in atherosclerosis and atherothrombosis. Therefore, an exosome‐based multifunctional nanomedicine for the diagnosis, monitoring, and treatment of these ...
Tuan Huu Nguyen   +4 more
wiley   +1 more source

Assessment of Blood Profiles and Pain in Sport Horses Undergoing Intrarectal Ozone Therapy

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Ozone therapy influenced haemoglobin, MCHC, and AST activity in horses, with transient red blood cell deformities and increased pain scores observed. No clinical symptoms or liver damage occurred. Findings suggest that lower ozone concentrations may reduce treatment‐related discomfort while maintaining therapeutic effects.
Thamirys Dias de Luna Paiva   +5 more
wiley   +1 more source

The Influence of Bromelain Administration on Pro‐Inflammatory Cytokines and Lipid Peroxidation in a Rat Model of Intestinal Ischemia/Reperfusion Injury

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Bromelain reduces levels of the pro‐inflammatory cytokines TNF‐α, IL‐1β and MDA in intestinal ischemia‐reperfusion injury. Bromelain's effects on cytokines also reduce damage to intestinal tissue.2 ABSTRACT Background Ischemia‐reperfusion injury is a critical problem that can occur following multiple clinical procedures.
Çağrı Gültekin   +3 more
wiley   +1 more source

Nanoparticles‐Mediated Modulation of TRP Channels: Advances and Therapeutic Potential

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.
Nanoparticle‐mediated modulation of TRP channels, highlighting the interplay between external stimuli, tailored nanomaterials, and TRP channel activation across a range of physiological contexts. This review examines the roles of TRP channels in cellular signaling and disease, providing insights into how advances in nanotechnology can facilitate ...
Karina A. Foster   +3 more
wiley   +1 more source

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