ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu +5 more
wiley +1 more source
<i>In situ</i> post-ischemic conditioning by temporary balloon occlusion for acute ischemic stroke: a modified reperfusion technique and adverse event monitoring. [PDF]
Wang S +5 more
europepmc +1 more source
Exosomes (small extracellular vesicles) are nanosized vesicles produced naturally by living cells. They can be engineered by various techniques to deliver biologically active molecules to injury sites in atherosclerosis and atherothrombosis. Therefore, an exosome‐based multifunctional nanomedicine for the diagnosis, monitoring, and treatment of these ...
Tuan Huu Nguyen +4 more
wiley +1 more source
Significance of Subtle Diffusion Weighted Imaging Lesion Dynamics: A Comparative Analysis of Methods for Detecting Diffusion Weighted Imaging Lesion Reversal in Endovascular Stroke Treatment. [PDF]
Skattør TH +8 more
europepmc +1 more source
Assessment of Blood Profiles and Pain in Sport Horses Undergoing Intrarectal Ozone Therapy
Ozone therapy influenced haemoglobin, MCHC, and AST activity in horses, with transient red blood cell deformities and increased pain scores observed. No clinical symptoms or liver damage occurred. Findings suggest that lower ozone concentrations may reduce treatment‐related discomfort while maintaining therapeutic effects.
Thamirys Dias de Luna Paiva +5 more
wiley +1 more source
Hemichorea as a Manifestation of Isolated Insular Infarction Successfully Treated with Mechanical Thrombectomy. [PDF]
Romozzi M +4 more
europepmc +1 more source
Bromelain reduces levels of the pro‐inflammatory cytokines TNF‐α, IL‐1β and MDA in intestinal ischemia‐reperfusion injury. Bromelain's effects on cytokines also reduce damage to intestinal tissue.2 ABSTRACT Background Ischemia‐reperfusion injury is a critical problem that can occur following multiple clinical procedures.
Çağrı Gültekin +3 more
wiley +1 more source
Chronic ischemic heart disease: A nonuniform syndrome. [PDF]
Alam S, Pepine CJ.
europepmc +1 more source
Nanoparticles‐Mediated Modulation of TRP Channels: Advances and Therapeutic Potential
Nanoparticle‐mediated modulation of TRP channels, highlighting the interplay between external stimuli, tailored nanomaterials, and TRP channel activation across a range of physiological contexts. This review examines the roles of TRP channels in cellular signaling and disease, providing insights into how advances in nanotechnology can facilitate ...
Karina A. Foster +3 more
wiley +1 more source
Differential impact of deep intraparenchymal hyperdensities versus subarachnoid/cortical hyperdensities on futile reperfusion after mechanical thrombectomy: a propensity score-matched study. [PDF]
Dong M +5 more
europepmc +1 more source

