Results 151 to 160 of about 21,570 (177)

Insights Into Macrophage Polarization and M1/M2 Balance in Diabetic Foot Ulcers

Journal of Diabetes, Volume 18, Issue 3, March 2026.
This graphical abstract illustrates pharmaceutical agents that modulate M1/M2 macrophage polarization in diabetic foot ulcers (DFUs). M1 macrophages (red) drive inflammation, whereas M2 macrophages (blue) promote tissue repair. In DFUs, persistent M1 predominance contributes to chronic non‐healing. Five key agents targeting this imbalance are depicted:
Jing Zhang, Hong Li, Yulin Dong, Zhuoyan Zhou, Yuhan Wang, Xia Chen, Yulan Cai   +6 more
wiley   +1 more source

Sex Differences in Prognostic Markers: Exploring Outcome Variability After Mechanical Thrombectomy in Large Vessel Occlusion Stroke. [PDF]

J Clin Med
Schacht H, Neumann A, Petersen N, Ehm LM, Marburg M, Matthis C, Jensen-Kondering U, Schramm P, Minnerup J, Royl G, Koch PJ.   +10 more
europepmc   +1 more source

Inferior‐Lead Lambda (λ) Wave Revealing Critical Right Coronary Artery Stenosis: A Case Report

Annals of Noninvasive Electrocardiology, Volume 31, Issue 2, March 2026.
Lambda (λ) wave pattern observed in the inferior leads (II, III, aVF) associated with critical 95% stenosis of the right coronary artery. Percutaneous coronary intervention with drug‐eluting stent deployment resulted in complete resolution of the λ wave abnormality and long‐term clinical stability from 2020 to 2024.
Jian Xiong, Djandan Tadum Arthur Vithran, Jingjing Chai, Zheng Cao, Zhixiao Wang, Xiaoyong Hu   +5 more
wiley   +1 more source

Adjusting input arterial function to improve the accuracy of hypoperfusion assessment in computed tomography perfusion (CTP) for stroke: a preliminary study. [PDF]

Quant Imaging Med Surg
Hu H, Zeng F, Huang Y, Zheng J, Xing Z, Ye Q, Lin L, Xue Y.   +7 more
europepmc   +1 more source

Stroke burden and functional impacts in adults with sickle cell disease

British Journal of Haematology, Volume 208, Issue 3, Page 1063-1073, March 2026.
Stroke was identified in 4.6% of 454 adults with sickle cell disease. Stroke occurred not only across HbSS/Sβ0 phenotypes but also HbSC/Sβ+ as well, challenging traditional assumptions. Stroke was associated with long‐term functional impairment, including cognitive deficits and higher disability scores.
Jonathan St‐Onge, Tzvetena Hristova, Chrystelle Charles, Olena Bereznyakova, Gregory Jacquin, Olivier Pouliot, Janick Caron‐Lecuyer, Mia Stevanovik, Sara‐Maude Desforges, Costa M. Kazadi, Julian Alejandro Rivillas, Christian Stapf, Stéphanie Forté   +12 more
wiley   +1 more source

Non‐Pulmonary Mechanisms of Action of Ambroxol in In Vivo Experimental Models: a Systematic Review

Fundamental &Clinical Pharmacology, Volume 40, Issue 2, March 2026.
ABSTRACT Background Repositioning offers a cost‐effective approach to discovering new therapeutic applications for existing medications. Ambroxol, primarily used as a mucolytic for respiratory diseases, has demonstrated anti‐inflammatory, analgesic, and antioxidant properties, suggesting potential benefits in non‐pulmonary conditions.
Michelline Joana Tenório Albuquerque Madruga Mesquita, Anne Caroline Silva Nogueira da Cruz, Rafael de Abreu Lima, Joana Tenório‐Meireles, Arney José Nogueira Farias, Isabela Nogueira Santos, Gustavo Frota, Taciana Gabrielle Pinheiro de Moura Carvalho, Rafael Antônio Freire Carvalho, Jorge Antônio Meireles‐Teixeira, Tereza Prazeres, Rafael Cardoso Carvalho, Maria do Socorro de Sousa Cartágenes, João Batista Santos Garcia   +13 more
wiley   +1 more source

CORM-A1 delivers carbon monoxide to the kidney and alleviates post-ischemic renal dysfunction in rat and swine models. [PDF]

Physiol Rep
Foresti R, Shurey S, Mao Q, Kitagishi H, Green CJ, Motterlini R.   +5 more
europepmc   +1 more source

Regional perfusion parameters as potential indicators of parenchymal hematoma risk following reperfusion therapy for acute ischemic stroke in the extended time window. [PDF]

Ther Adv Neurol Disord
Liu X, Hong L, Zhao G, He Z, Wang X, Zhu J, Li S, Zhang A, Cao N, Ling Y, Chen X, Guo Y, Fang Q, Wang Z, Dong Q, Cheng X.   +15 more
europepmc   +1 more source

Delayed CPK peak after primary PCI in STEMI: marker of reperfusion quality and short-term outcomes. [PDF]

BMC Cardiovasc Disord
Umehara E, Nagase Y, Yao S, Nagasawa K, Kobayashi N, Asakura Y, Miyajima A, Inoue N, Hagikura A, Kusuyama T, Iida H.   +10 more
europepmc   +1 more source

Optimized dose of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke. [PDF]

Brain Res
Jiang Z, Alamuri TT, Yang DL, Annarino T, Muir ER, Duong TQ.   +5 more
europepmc   +1 more source