Results 101 to 110 of about 69,255 (306)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The finger lesion [PDF]

Internal and Emergency Medicine, 2015
Pouya, Entezari, Ameneh, Alaini, Yahya, Daneshbod, Hadi, Mirfazaelian   +3 more
openaire   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Reparación de lesiones corticales: dianas, mecanismos y oportunidades terapéuticas [PDF]

Las lesiones cerebrales de diversas etiologías cursan con una pérdida irreversible de neuronas que conlleva la aparición de déficits cognitivos motores y sensoriales. El conocimiento de los mecanismos de reemplazo neuronal en el cerebro adulto ha abierto
Nunez Abades, Pedro, Ortego Domínguez, María, Domínguez García, Samuel, Chamorro Francisco, Andrea, Martínez-Gómez, Nora, Carrascal, Livia, Pérez García, Patricia, Vázquez de Górgolas, Sonia, Castro González, Carmen, Pardillo Díaz, Ricardo, Gómez Oliva, Ricardo   +10 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Pielografía endovenosa con el Uroselectan

Cirugía del Uruguay, 2019
Presentado en la Sesión del 6 de Agosto de ...
E Lorenzo, B Varela Fuentes, P Rubino
doaj  

Janeway lesion [PDF]

QJM: An International Journal of Medicine, 2020
T, Gailson, S, Pandit, S, Rathi
openaire   +2 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Traumatismos de la vena cava inferior (Subhepática)

Cirugía del Uruguay, 1989
Con motivo de la presentación de 7 casos inéditos se revisan 22 casos de traumatismo de la Vena Cava Inferior subhepática publicados en la literatura nacional. Se destaca una baja frecuencia lesiona! con un incremento progresivo de su incidencia. La edad
Roberto Estrugo
doaj